PERMA模式下协同行为干预对淋巴瘤化疗患者癌因性疲乏、生活质量的影响

Effects of collaborative behavioral intervention under PERMA mode on cancer-related fatigue and quality of life in lymphoma patients undergoing chemotherapy

目的探讨PERMA模式下协同行为干预对淋巴瘤化疗患者癌因性疲乏、生活质量的影响。方法根据干预方案的不同将108例淋巴瘤化疗患者分为研究组(n=50)和对照组(n=58),对照组患者接受常规干预,研究组患者接受PERMA模式下协同行为干预。比较两组患者的癌因性疲乏程度[Piper疲乏量表(PFS)]、生活质量[癌症患者生命质量测定量表(QLICP)]及不良反应发生情况。结果干预后,两组患者PFS各维度评分均低于本组干预前,研究组患者PFS各维度评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者QLICP各维度评分均高于本组干预前,研究组患者QLICP各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。研究组患者不良反应总发生率为8.00%,低于对照组患者的22.41%,差异有统计学意义(P﹤0.05)。结论PERMA模式下协同行为干预能明显减轻淋巴瘤化疗患者的癌因性疲乏程度,提高生活质量,降低化疗期间不良反应发生率。

Objective To explore the effects of collaborative behavioral intervention under PERMA mode on cancerrelated fatigue and quality of life in lymphoma patients undergoing chemotherapy.Method According to different intervention plans,108 lymphoma patients who received chemotherapy were divided into study group(n=50)and control group(n=58).Patients in the control group received routine intervention,while patients in the study group received collaborative behavioral intervention under PERMA mode.The cancer-related fatigue degree[Piper fatigue scale(PFS)],quality of life[quality of life instruments for cancer patients(QLICP)],and incidence of adverse reactions were compared between the two groups.Result After intervention,the scores of all dimensions of PFS in both groups were lower than those before intervention,the scores of all dimensions of PFS in study group were lower than those in control group,and the differences were statistically significant(P<0.05).After intervention,the scores of all dimensions of QLICP in both groups were higher than those before intervention,the scores of all dimensions of QLICP in study group were higher than those in control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the study group was 8.00%,which was lower than 22.41%in the control group,and the difference was statistically significant(P<0.05).Conclusion Collaborative behavioral intervention under PERMA mode can significantly reduce the degree of cancer-related fatigue in lymphoma patients undergoing chemotherapy,enhance their quality of life,and reduce adverse reactions during chemotherapy.