钙剂联合维生素D治疗儿童营养性维生素D缺乏性佝偻病合并缺铁性贫血的临床效果分析

Clinical Effect of Calcium Combined with Vitamin D in the Treatment of Nutritional Vitamin D Deficiency Rickets with Iron Deficiency Anemia in Children

目的:分析儿童营养性维生素D缺乏性佝偻病合并缺铁性贫血采取钙剂联合维生素D治疗的临床效果。方法:选取2021年1月—2022年12月惠民县卫生健康保障中心门诊收治的儿童营养性维生素D缺乏性佝偻病合并缺铁性贫血患儿150例作为研究对象,以抽签法随机分为对照组和观察组,各75例。对照组采取常规补充维生素D和铁剂治疗,观察组在对照组基础上给予碳酸钙D3治疗。比较两组患者临床疗效、血红蛋白水平、营养指标、缺铁性贫血纠正时间、不良反应发生情况。结果:治疗后,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。两组白蛋白、总蛋白和血红蛋白高于治疗前,观察组高于对照组,差异有统计学意义(P<0.05)。观察组缺铁性贫血纠正时间短于对照组,差异有统计学意义(P<0.001)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在儿童营养性维生素D缺乏性佝偻病合并缺铁性贫血患儿的临床治疗中,采取综合治疗具有较高的应用价值,能够改善患儿的营养指标,促进病情恢复,且具有较高的安全性。

Objective:To analyze the clinical effect of calcium combined with vitamin D in the treatment of nutritional vitamin D deficiency rickets complicated with iron deficiency anemia in children.Methods:A total of one hundred and fifty children with nutritional vitamin D deficiency rickets combined with iron deficiency anemia admitted to the outpatient department of Huimin County Health Care Center from January 2021 to December 2022 were selected as the study objects,and were divided into control group and observation group by random drawing method,with seventy-five cases in each group.The control group was treated with vitamin D and iron supplement,and the observation group was treated with calcium carbonate D3 on the basis of control group.The clinical efficacy,hemoglobin level,nutritional indexes,correction time of iron deficiency anemia and occurrence of adverse reactions were compared between the two groups.Results:After treatment,the total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05);albumin,total protein and hemoglobin in 2 groups were higher than before treatment,and observation group was higher than control group,the difference was statistically significant(P<0.05);the correction time of iron deficiency anemia in observation group was shorter than that in control group,and the difference was statistically significant(P<0.001);there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:In the clinical treatment of children with nutritional vitamin D deficiency rickets complicated with iron deficiency anemia,comprehensive treatment has high application value,can improve the nutritional indexes of children,promote the recovery of the disease,and has high safety.