多模态磁共振成像在儿童癫痫中的应用进展

Advances in the application of multimodal magnetic resonance imaging in childhood epilepsy

癫痫是一种广泛存在的神经系统疾病, 任何可能影响脑结构和功能的病理过程均可引起发作。它并不代表一种独特的实体, 而是一组不同的病理。早发现、早诊断是控制癫痫进展、改善预后的关键。磁共振成像(MRI)因无电离辐射损伤、极佳的软组织分辨力及空间分辨率, 是临床公认的癫痫检查方法。随着磁共振设备的升级及新型成像技术的开放应用, 如综合多种磁共振序列的多模态MRI, 以其多参数成像、高空间分辨率, 彻底改变了检测病变的能力, 使得在解剖结构、分子水平、生化代谢各个方面对癫痫的认识取得了长足的进步。现就多模态MRI技术在儿童癫痫的应用进展进行综述。

Epilepsy is a widespread neurological disease,which can be caused by any pathological process that may affect the structure and function of the brain.It encompasses a spectrum of pathologies rather than a singular entity.Early detection and diagnosis is the key to controlling the progression of epilepsy and improving the prognosis.Magnetic resonance imaging(MRI)is a clinically recognized method for the examination of epilepsy because of its non-ionizing radiation damage and excellent soft tissue resolution and spatial resolution.With the upgrading of MRI equipment and the open application of new imaging technologies,such as multimodal MRI that integrates multiple magnetic resonance sequences,its multi-parameter imaging and high spatial resolution have completely changed the ability to detect lesions,making significant progress in understanding epilepsy from the anatomical structure,molecular level,and biochemical metabolism.This article reviews the advances in the application of multimodal MRI technology in childhood epilepsy.