铁对畜禽肠道屏障的影响及作用机制研究进展

Research Progress on Effects and Mechanisms of Iron on Intestinal Barrier in Livestock and Poultry

肠道屏障的完整性对于动物的健康和生产性能至关重要。铁作为一种必需微量矿物元素,不仅在维持正常生理功能中起着关键作用,还与肠道屏障的完整性紧密相关。适量铁对肠道屏障有保护作用,而缺铁和高剂量铁均可能对肠道屏障的完整性和功能产生不良影响。本文介绍了铁的生物学功能,综述了铁对肠道屏障的影响以及可能涉及的作用机制,旨在为生产中合理利用铁制剂提供理论参考。

The intestinal barrier integrity is essential for the health and performance of animals.Iron,as an essential trace element,not only plays a key role in maintaining normal physiological functions,but also is closely related to the integrity of the intestinal barrier.Moderate iron intake has a protective effect on the intestinal barrier,while both deficiency and excess of iron may adversely affect the integrity and function of the intestinal barrier.In this paper,the biological functions of iron,its effects on intestinal barrier and the possible mechanisms involved were reviewed,so as to provide theoretical reference for rational use of iron preparations in production.