巴宁猪不同生长阶段血液生理生化、免疫和抗氧化指标比较分析

Comparative Analysis of Blood Physiological,Biochemical,Immune,and Antioxidant Indicators in Baning Pigs in Different Growth Stages

该试验以42头健康、初生体重为1 kg左右的半同胞代的巴宁猪为研究对象,按0、2、4、6、8、10和12月龄分为7个生长阶段,分别对13项血液生理指标、16项血清生化指标、5项激素指标、9项免疫因子指标和5项抗氧化指标的含量进行检测分析。结果表明:血液生理指标中,4、6和8月龄的平均红细胞体积和平均红细胞血红蛋白含量均显著低于其他月龄(P<0.05)。血清生化指标中,白蛋白、总胆固醇、高密度脂蛋白、低密度脂蛋白、丙氨酸氨基转移酶和葡萄糖的含量均在2月龄最高,总蛋白含量在6月龄最高。总蛋白、白蛋白、碱性磷酸酶、血尿素氮、葡萄糖、甘油三酯和丙氨酸氨基转移酶均与月龄存在关联;总蛋白与白蛋白、球蛋白、血尿素氮、葡萄糖间存在极显著相关(P<0.01)。总胆固醇与高密度脂蛋白、低密度脂蛋白、丙氨酸氨基转移酶存在极显著相关(P<0.01)。激素指标中,皮质醇、胰岛素和甲状腺素的含量分别在4、6和8月龄时最高。免疫因子指标中,4月龄白细胞介素2显著高于6月龄,2月龄的IgA显著高于0月龄,12月龄的IgG显著高于8月龄(P<0.05)。抗氧化因子指标中,12月龄的超氧化物歧化酶显著高于8月龄(P<0.05)。可见,巴宁猪血液生化指标及月龄间均存在普遍关联,巴宁猪在6和8月龄阶段分别为造血功能和肌肉发育的高峰期,应制定相应的营养管理与饲喂策略。不同生长阶段对血液生理生化指标和激素指标的含量影响较大,对免疫因子指标和抗氧化因子指标的含量影响较小。

In this experiment,42 healthy half-sib-banning pigs with a birth weight of about 1 kg were used as the research objects.They were divided into 7 growth stages according to the age of 0,2,4,6,8,10,and 12 months.The contents of 13 blood physiological indicators,16 serum biochemical indicators,5 hormone indicators,9 immune factor indicators,and 5 antioxidant indicators were detected and analyzed respectively.The results showed that among blood physiological indicators,the average red cell volume and hemoglobin content at 4,6,and 8 months were significantly lower than those at other months(P<0.05).Among serum biochemical indicators,the contents of albumin,total cholesterol,high-density lipoprotein,low-density lipoprotein,alanine aminotransferase,and glucose were the highest at 2-month-old,and the total protein content was the highest at 6-month-old.Total protein,albumin,alkaline phosphatase,blood urea nitrogen,glucose,triglycerides,and alanine aminotransferase were all associated with age;there was a very significant correlation between total protein and albumin,globulin,blood urea nitrogen,and glucose(P<0.01).Total cholesterol was significantly correlated with high-density lipoprotein,low-density lipoprotein,and alanine aminotransferase(P<0.01).Among hormone indicators,the contents of cortisol,insulin,and thyroxine were highest at 4,6,and 8-month-old respectively.Among the immune factor indicators,interleukin-2 at 4-month-old was significantly higher than at 6-month-old,IgA at 2-month-old was significantly higher than that at 0-month-old,and IgG at 12-month-old was significantly higher than that at 8-month-old(P<0.05).Among the antioxidant factor indicators,the superoxide dismutase at 12 months old was significantly higher than that at 8 months old(P<0.05).It can be seen that there is a general correlation between blood biochemical indicators and the age of Banning pigs.Banning pigs are at the peak of hematopoietic function and muscle development at 6 and 8-month-old,respectively.Corresponding nutritional management and feeding strategies should be formulated.Different growth stages have a greater impact on the content of blood physiological,biochemical,and hormone indicators,and have a lesser impact on the content of immune factor indicators and antioxidant factor indicators.