摘要
溴吡斯的明是治疗重症肌无力(MG)的一线药物,但临床上并非所有亚型MG均能获得良好的治疗效果,尤其是在幼儿、青少年、孕妇等特殊群体中的安全性和有效性有待探讨。本文就溴吡斯的明治疗MG的不良反应和目前存在的临床问题进行阐述,并提出可能的解决措施,以期为后续完善MG治疗方案提供借鉴。
Pyridostigmine bromide is a first-line drug for the treatment of myasthenia gravis(MG).In clinical application,its therapeutic effects are not good on all subtypes of MG,especially in the treatment of special groups for which no norms can yet be found.This article elaborates on the adverse reactions and current clinical problems of pyridostigmine bromide in the treatment of MG,and proposes possible solutions to provide reference for improving MG treatment plans in the future.
作者
代德金
赵杨
吴天晨
梁艳
杨卉
DAI Dejin;ZHAO Yang;WU Tianchen;LIANG Yan;YANG Hui(Department of Neurology,Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210001,China;Nursing School,Nanjing University of Chinese Medicine,Naijing 210023,China)
出处
《药学与临床研究》
2024年第4期355-358,共4页
Pharmaceutical and Clinical Research
基金
国家自然科学基金(81904112)
江苏省自然科学基金(BK20190136)
南京市卫生科技发展专项医学重点科技发展项目(ZKX20050)。
关键词
溴吡斯的明
重症肌无力
不良反应
临床问题
Pyridostigmine bromide
Myasthenia gravis
Adverse reactions
Clinical problem