1例脓毒血症继发肺曲霉菌感染患者的药学监护

Pharmaceutical care of pulmonary aspergillus infection secondary to sepsis

目的 探讨临床药师在抗感染治疗过程中的作用,为临床提供药学监护与个体化治疗积累实践经验,促进临床合理用药。方法 临床药师参与1例脓毒血症继发肺曲霉菌感染患者的抗感染治疗全过程。协助临床医师制定和调整治疗方案,对伏立康唑片进行血药浓度监测并提供个体化给药方案及药学监护。结果 患者病情得到好转,为以后提供更好的药学服务积累了经验。结论 临床药师积极参与脓毒血症继发肺曲霉菌感染的药物治疗实践,保证了患者药物治疗的有效性及安全性,充分体现了临床药师的自身价值。

Objective To explore the role of clinical pharmacists in the course of anti-infection treatment,and exchange experience related to individualized treatment of patients with pulmonary aspergillus infection secondary to sepsis so as to promote clinical rational drug use.Methods Clinical pharmacists participated in the whole process of anti-infection treatment of a patient with pulmonary aspergillus infection secondary to sepsis by assisting clinicians in formulating and adjusting treatment plans,monitoring voriconazole concentrations in blood,and providing individualized medications and pharmaceutical care.Results The condition of the patient was improved eventually,which offered experience for providing better pharmaceutical care in the future.Conclusion Clinical pharmacists’participation in medications against pulmonary aspergillus infection secondary to sepsis can help ensure the effectiveness and safety of drug treatment for patients so that the worth of clinical pharmacists can be proved.