基于CiteSpace可视化分析国内外蒲公英防治肿瘤研究现状及趋势

The research status and trend of dandelion in the prevention and treatment of tumors at home and abroad based on CiteSpace

目的了解蒲公英防治肿瘤相关领域的研究热点与发展趋势。方法检索中国知网、万方数据知识服务平台、维普网及Web of Science核心数据库2000年1月1日—2023年11月24日收录的蒲公英防治肿瘤相关文献,应用CiteSpace软件对作者、发文机构及关键词进行可视化分析。结果纳入中文文献663篇,英文文献120篇,年发文量呈总体上升趋势。中文文献提取作者698人、机构336个,英文文献提取作者317人、机构189个。提取中文关键词593个,排名前5位的依次为蒲公英、化学成分、乳腺癌、药理作用、用药规律;提取英文关键词337个,排名前5位的依次为apoptosis、dandelion、taraxacum officinale、activation、expression。结论蒲公英防治肿瘤相关研究受到国内外的持续关注,中文文献研究热点为网络药理学、用药规律、数据挖掘等;英文文献研究热点为antioxidant、selective induction、hepatocelluar carcinoma等,总体来说临床研究较少,建议加强基础研究与临床的联系,着力转化研究,充分发掘中药的治疗价值。

Objective To investigate the research hotspots and development trends of dandelion in the field of cancer prevention and treatment.Methods The relevant literature on the prevention and treatment of tumors with dandelion was retrieved from China National Knowledge Infrastructure,Wanfang Data,VIP website,and Web of Science core databases from January 1,2000 to November 24,2023.The CiteSpace software was used to visualize the authors,publishing institutions,and keywords.Results Totally,663 Chinese papers and 120 English papers were included,and the annual number of publications showed an overall upward trend.There were 698 authors and 336 institutions extracted from Chinese papers,and 317 authors and 189 institutions from English papers.A total of 593 Chinese keywords were extracted,and the top five were dandelion,chemical composition,breast cancer,pharmacological effects,and drug rules.A total of 337 English keywords were extracted,and the top five were apoptosis,dandelion,taraxacum officinale,activation,and expression.Conclusion The research on the prevention and treatment of tumors with dandelion has received continuous attention at home and abroad.The research hotspots of Chinese literature were network pharmacology,drug use rules,data mining,etc.The research hotspots in English literature were antioxidant,selective induction,hepatocellular carcinoma,etc.In general,there were relatively less clinical studies,so it is recommended to strengthen the connection between basic research and clinical practice,focus on translational research,and explore fully the therapeutic value of traditional Chinese medicine.