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基于“肺肠相表里”理论探讨肠道菌群与肺病防治

Relationship Between Gut Microbiota and Lung Disease Prevention and Treatment Based on Theory of"Interaction between Lung and Large Intestine"
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摘要 本文探讨了中医“肺与大肠相表里”理论在现代科学研究中的体现。该理论认为肺与大肠在生理和病理上紧密相连,并指出在治疗肺系疾病时可通过调节肠道实现。现代研究揭示了两者间微生物的相互作用,提出了基于肠道微生物的“肺-肠轴”概念,为中医理论提供了科学阐释。通过大量的文献研究揭示肠道菌群在肺系疾病发生、发展及中医药治疗中的变化规律,深入分析了肠道菌群、中药与肺系疾病之间的关联性和作用机制。本文旨在为肺系疾病的微生物治疗提供新思路,并为中药的现代化研究开辟新途径,以期更好地服务于人类健康。 This article explored the modern scientific applic ation of the"interaction between lung and large intestine" theory. This theory posits that the lungs and large intestine areintimately connected both physiologically and pathologically and suggests that by regulatingthe gut, pulmonary diseases can be treated. Modern research has unveiled the interactionbetween the microbiota of the two organs and introduced the concept of the "lung-gut axis"based on gut microbiota, thereby providing a scientific interpretation of traditional Chinesemedicine theories. Based on extensive literature research, the changes in gut microbiota duringthe occurrence, development, and treatment of pulmonary diseases by traditional Chinesemedicine were revealed, and the correlation and mechanism of action among gut microbiota,traditional Chinese medicine, and pulmonary diseases were analyzed. This article aims tooffer novel approaches for microbial therapy of pulmonary diseases and pioneer new paths forthe modernization of traditional Chinese medicine research, so as to better guarantee humanhealth.
作者 朱杰 刘嘉 曾明月 曾庆琪 张可可 刑泽斌 ZHU Jie;LIU Jia;ZENG Mingyue;ZENG Qingqi;ZHANG Keke;XING Zebin(Jiangsu Health Vocational College Integrated Traditional Chinese and Western Medicine College,Nanjing 211800,China;School of Pharmacy,Beijing University of Chinese Medicine,Beijing 100029,China;The First Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China)
出处 《基层中医药》 2024年第9期61-66,共6页 Basic Traditional Chinese Medicine
基金 江苏高校哲学社会科学研究一般项目(2021SJA0839) 江苏高校“青蓝工程” 江苏卫生健康职业学院校级课题重点项目(JKB201905) 江苏卫生健康职业学院校级教学成果奖培育项目。
关键词 肠道菌群 肺-肠轴 肺炎 肺与大肠相表里 gut microbiota lung-gut axis pneumonia interaction between lung and large intestine
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