红光辅助醋酸泼尼松治疗亚急性甲状腺炎的效果

Effect of Red Light Assisted Prednisone Acetate in the Treatment of Subacute Thyroiditis

目的:探讨红光联合激素治疗亚急性甲状腺炎(SAT)的效果。方法:选取2020年2月—2023年5月本院诊治的SAT患者62例进行对照研究,采用随机数字表法分为联合组与对照组,每组31例。对照组予以醋酸泼尼松口服治疗,联合组在对照组基础上联合红光治疗。比较两组症状消失时间、血清甲状腺功能指标(TSH、FT3、FT4)、炎症指标(ESR、CRP、IL-6)、醋酸泼尼松累计量、不良反应率及随访复发率。结果:治疗后,观察组颈部疼痛、发热及甲状腺肿大消失时间低于对照组(P<0.05);观察组FT3、FT4低于对照组,TSH高于对照组(P<0.05);观察组ESR、CRP、IL-6低于对照组(P<0.05);观察组醋酸泼尼松累计用量、不良反应发生率均低于对照组(P<0.05);两组复发率比较,差异无统计学意义(P>0.05)。结论:红光联合醋酸泼尼松治疗AST的效果较好,能有效改善临床症状,缩短病情缓解时间,减少泼尼松用量及不良反应发生率。

Objective:To investigate the effect of red light combined with hormone in the treatment of subacute thyroiditis(SAT).Methods:A total of 62 SAT patients diagnosed and treated in our hospital from February 2020 to May 2023 were selected for comparative study.They were divided into combined group and control group by random number table method,with 31 patients in each group.The control group was treated with prednisone acetate orally,and the combined group was treated with red light on the basis of the control group.The disappearance time of symptoms,serum thyroid function indexes(TSH,FT3,FT4),inflammatory indexes(ESR,CRP,IL-6),cumulative amount of prednisone acetate,adverse reaction rate and follow-up recurrence rate were compared between the two groups.Results:After treatment,the disappearance time of neck pain,fever and goiter in the observation group was lower than that in the control group(P<0.05).FT3 and FT4 in the observation group were lower than those in the control group,and TSH was higher than that in the control group(P<0.05).ESR,CRP and IL-6 in the observation group were lower than those in the control group(P<0.05).The cumulative dosage of prednisone acetate and the incidence of adverse reactions in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the recurrence rate between the two groups(P>0.05).Conclusion:Red light combined with prednisone acetate is effective in the treatment of AST,which can effectively improve the clinical symptoms,shorten the remission time,reduce the dosage of prednisone and the incidence of adverse reactions.