聚多巴胺包覆Zn-Ti水滑石的制备、抗紫外性能及其在日化防晒中的应用

Preparation and Anti-Ultraviolet Performance of Polydopamine Coated Zn-Ti Layered Double Hydroxide with Application in Sunscreen and Daily Chemical Industry

传统防晒剂,特别是二苯甲酮等有机紫外吸收剂,由于其具有很强的光活性和皮肤渗透性,可能会对人体造成一些损伤,甚至诱发癌症。因此,开发高效且安全的新型防晒剂具有重要实际意义。以无水醋酸锌(Zn(Ac)_(2))、四氯化钛(TiCl_(4))和盐酸多巴胺为原料,以乙醇/水溶液为溶剂,利用水热法制备了聚多巴胺(PDA)包覆的Zn-Ti水滑石(P@ZTL)复合粒子,并将其作为唯一防晒组分制备防晒霜样品。对P@ZTL的化学结构、组成、微观形貌、抗紫外性能、自由基清除性能及细胞毒性进行了研究,并对防晒霜样品的防晒性能进行了测试。结果表明,P@ZTL的结构为粒径1~5μm的PDA包覆ZTL复合粒子,比表面积为145.916 m^(2)/g;复合粒子具有典型的介孔结构,孔隙率为0.154 cm^(3)/g;复合粒子具备高效紫外吸收和活性氧自由基清除能力,且无细胞毒性;由P@ZTL制得的防晒霜具有优异的防晒性能,能够保护成纤维细胞在紫外光照射下保持形态并存活,并且添加了质量分数10%和15%P@ZTL的防晒霜样品的防晒指数(SPF)分别达到了47.3±2.3和75.1±3.1,完全可以满足日常防晒需求。因此,合成的P@ZTL防晒剂在化妆品领域具有很大的应用前景。

Traditional sunscreens,especially organic ultraviolet(UV)absorbers such as benzophenone,have strong photoactivity and skin permeability,which may cause some human injuries and even cancer.Therefore,it is of great practical significance to develop efficient and safe new sunscreen.With anhydrous zinc acetate(Zn(Ac)_(2)),titanium tetrachloride(TiCl_(4))and dopamine hydrochloride as raw materials and ethanol/water solution as solvent,polydopamine(PDA)coated Zn-Ti layered double hydroxide(P@ZTL)compounded particles were synthesized through a hydrothermal method.Afterwards,sunscreen samples were prepared with them as the only UV-blocking component.The chemical structure,composition and micromorphology,along withUV absorbance,free radical scavenging and cytotoxicity performance of P@ZTL were studied.Indispensably,the UV-blocking properties of the sunscreen samples were tested.The results showed that the structure of P@ZTL was 1~5μm PDA coated ZTL compounded particles,with a specific surface area of 145.916 m^(2)/g.The particles had a typical mesoporous structure with a porosity of 0.154 cm^(3)/g.The compounded particles had great UV absorption and reactive oxygen species(ROS)scavenging abilities,along with no cytotoxicity.The sunscreen with P@ZTL had excellent UV protecting performance,which could preserve fibroblasts from direct UV irradiation.The sun protection index(SPF)values of sunscreen samples added with 10%and 15%P@ZTL reached 47.3±2.3 and 75.1±3.1,respectively,which could fully meet the daily use.Therefore,the synthesized P@ZTL sunscreen has a great application prospect in cosmetics.