摘要
微针疗法是一种微创治疗技术,通过刺激头皮诱导损伤后自我修复级联反应,促进生长因子和细胞因子的释放,改善毛囊状态并促进毛发生长。微针疗法与局部药物、富血小板血浆/富血小板纤维蛋白(PRP/PRF)、口服西药和中药等联合应用,能显著提高脱发治疗的有效率。其中,微针联合局部药物是目前临床应用最常见的治疗方案,其他联合治疗方法的临床研究仍相对较少,需要更多的研究数据来证实其疗效。尽管微针疗法在脱发治疗中具有一定优势,但其疗效存在个体差异,且患者需要接受疗程化治疗。总体而言,微针疗法联合其他治疗方法对于改善脱发具有重要的价值,值得进一步研究和推广。该文综述微针疗法在脱发治疗中的应用及其联合治疗的优势和局限性。
Microneedling is a minimally invasive therapeutic technique that improves follicular status and promotes hair growth by stimulating the scalp to induce a post-injury self-repairing cascade response and promoting the release of growth factors and cytokines.The combination of microneedling with topical medications,platelet-rich plasma/platelet-rich fibrin(PRP/PRF),oral western and traditional Chinese medicine can significantly increase the effectiveness of hair loss treatment.Among them,the combination of microneedling with topical medications is the most common treatment option in clinical practice,while there are still relatively few clinical studies on other combined treatment,necessitating further research to substantiate their efficacy.Despite the inherent advantages of microneedling in the treatment of hair loss,its efficacy exhibits interindividual variability,necessitating tailored therapeutic interventions for patients.Overall,microneedling therapy in combination with other treatment modalities is of great value in improving hair loss and warrants further research and dissemination.This article reviews the application of microneedle therapy in treating hair loss and discusses the advantages and limitations of combinnation therapy.
作者
赵良森
张泽荣
廖勇
ZHAO Liangsen;ZHANG Zerong;LIAO Yong(Drug and Medical Device Line Medical Affairs Department,Bloomage Biotechnology Corporation Limited,Beijing 100000,China)
出处
《实用皮肤病学杂志》
2024年第4期221-225,240,共6页
Journal of Practical Dermatology
基金
国家自然科学基金资助项目(83040)
北京市科技新星项目(Z6000049639)。
关键词
脱发
雄激素性脱发
微针
微针疗法
研究进展
联合治疗
Hair loss
Androgenetic alopecia
Microneedling
Microneedling therapy
Research progress
Combination therapy