2002—2019年黄浦区前列腺癌发病和死亡趋势

Trends in incidence and mortality of prostate cancer in Huangpu District from 2002 to 2019

目的了解2002—2019年上海市黄浦区前列腺癌发病和死亡的变化趋势,为完善前列腺癌防控策略提供依据。方法通过上海市肿瘤病例登记报告系统收集2002—2019年黄浦区男性前列腺癌发病和死亡资料,计算粗发病率、粗死亡率、35~64岁截缩率及0~74岁累积率;采用2000年第五次全国人口普查数据和Segi's 1960世界标准人口构成分别计算中国人口标化率(中标率)和世界人口标化率(世标率);采用年度变化百分比(APC)和平均年度变化百分比(AAPC)分析前列腺癌发病和死亡趋势。结果2002—2019年黄浦区前列腺癌发病2672例,粗发病率为33.35/10万,中标发病率为14.93/10万,世标发病率为12.37/10万,呈上升趋势(AAPC=7.675%、4.886%、4.983%,均P<0.05)。60~<70岁、70~<80岁男性前列腺癌发病率呈上升趋势(AAPC=4.554%、5.045%,均P<0.05)。前列腺癌死亡1214例,粗死亡率为15.15/10万,中标死亡率为6.01/10万,世标死亡率为4.61/10万,呈上升趋势(AAPC=5.500%、2.057%、1.784%,均P<0.05)。≥80岁男性前列腺癌死亡率呈上升趋势(AAPC=4.220%,P<0.05)。结论2002—2019年黄浦区男性前列腺癌发病率和死亡率均呈上升趋势,其中≥60岁男性的发病率呈上升趋势,加强≥60岁男性前列腺癌筛查。

Objective To investigate the trends in incidence and mortality of prostate cancer in Huangpu District,Shang⁃hai Municipality from 2002 to 2019,so as to provide insights into the prevention and treatment of prostate cancer.Methods The incidence and mortality of prostate cancer among men in Huangpu District from 2002 to 2019 were col⁃lected from the Shanghai Cancer Registry System.The crude incidence,crude mortality,truncated age-standardized inci⁃dence(aged 35 to 64 years)and cumulative incidence(aged 0 to 74 years)of prostate cancer were calculated.The Chi⁃nese Fifth National Population Census in 2000 and the Segi's world standard population in 1960 were used to calculate Chinese-standardized rate and world-standardized rate.The trends in incidence and mortality of prostate cancer were evaluated using annual percent change(APC)and average annual percent change(AAPC).Results A total of 2672 cases of prostate cancer were reported in Huangpu District from 2002 to 2019,and the crude incidence was 33.35/105,the Chinese-standardized incidence was 14.93/105 and the world-standardized incidence was 12.37/105(AAPC=7.675%,4.886%and 4.983%,all P<0.05).The incidence of prostate cancer among males at ages of 60 to<70 years and 70 to<80 years appeared increasing trends(AAPC=4.554%and 5.045%,both P<0.05).A total of 1214 deaths of pros⁃tate cancer were reported,and the crude mortality was 15.15/105,the Chinese-standardized mortality was 6.01/105 and the world-standardized mortality was 4.61/105(AAPC=5.500%,2.057%and 1.784%,all P<0.05).The mortality of pros⁃tate cancer among males at ages of 80 years and above appeared an increasing trend(AAPC=4.220%,P<0.05).Conclu⁃sions The incidence and mortality of prostate cancer appeared increasing trends in Huangpu District from 2002 to 2019,and the incidence among males at ages of 60 years and above also increased.The screening for prostate cancer among males at ages of 60 years and above should be strengthened.