肝细胞癌术后早期复发的高危因素及预测方法

High-risk factors for early postoperative recurrence of hepatocellular carcinoma and related prediction methods

肝细胞癌(HCC)是一种发病率、病死率较高的恶性肿瘤,尽管手术切除是可能治愈的方法,其预后依旧受到高复发率的影响。早期复发(术后2年内)被定义为真正的复发,通常由原发肿瘤肝内扩散引起。HCC早期复发的预后较晚期复发差。因此,充分了解早期复发的高危因素及预测方法对术前治疗方案的选择、术后随访及预后预测至关重要。本文旨在对HCC术后早期复发高危因素及预测方法进行综述。

Hepatocellular carcinoma(HCC)is a malignant tumor with high incidence and mortality rates,and although surgical resection is a possible method for cure,the prognosis of HCC is still affected by its high recurrence rate.Early recurrence(within 2 years after surgery)is defined as true recurrence and is usually caused by the intrahepatic spread of primary tumor.Early recurrence of HCC tends to have a poorer prognosis than late recurrence.Therefore,it is of great importance to fully understand the high-risk factors and prediction methods for early recurrence,which is essential to the selection of preoperative treatment regimens,postoperative follow-up,and prognosis.This article reviews the high-risk factors and prediction methods for early recurrence of HCC after surgery.