灵枢开阖浊毒针法配合中药外用治疗寒湿痹阻型膝骨关节炎的临床效果

Clinical effect of Lingshu Kaihe turbid-toxin acupuncture combined with external use of traditional Chinese medicine in the treatment of knee osteoarthritis caused by cold-damp obstruction

目的探讨灵枢开阖浊毒针法配合中药外用治疗寒湿痹阻型膝骨关节炎的临床效果。方法选取2023年1月至12月就诊于河北中医药大学第一附属医院骨伤三科且具备相关标准要求的130例寒湿痹阻型膝骨关节炎患者作为研究对象,应用交替分组法分为治疗组(65例)和对照组(65例)。治疗组采用灵枢开阖浊毒针法配合中药外用治疗,对照组采用中药外用治疗。分别在治疗前后记录两组的视觉模拟评分(VAS)、西安大略和麦克马斯特大学骨关节炎指数量表评分(WOMAC),以及白细胞介素-1(IL-1)和肿瘤坏死因子-α(TNF-α)水平,并比较两组的治疗效果。结果两组患者治疗后的VAS、WOMAC评分,以及IL-1、TNF-α水平均低于本组治疗前,且治疗组治疗后的VAS、WOMAC评分,以及IL-1、TNF-α水平均低于对照组,差异有统计学意义(P<0.05)。治疗组的总有效率高于对照组,差异有统计学意义(P<0.05)。结论灵枢开阖浊毒针法配合中药在寒湿痹阻型膝骨关节炎的临床治疗中效果确切,能够一定程度上缓解患者疾痛,且具有简便效廉的特点,值得研究与推广。

Objective To investigate the clinical effect of Lingshu Kaihe turbid-toxin acupuncture combined with external use of traditional Chinese medicine in the treatment of knee osteoarthritis caused by cold-damp obstruction.Methods A total of 130 knee osteoarthritis patients with cold-damp obstruction who were admitted to the Third Department of Orthopaedics and Traumatology,the First Affiliated Hospital of Hebei University of Chinese Medicine from January to December 2023 and met the relevant standard requirements were selected as the research objects.They were divided into treatment group(65 cases)and control group(65 cases)by alternating grouping method.The treatment group was treated with Lingshu Kaihe turbid-toxin acupuncture combined with external use of traditional Chinese medicine,and the control group was treated with external use of traditional Chinese medicine.Before and after treatment,the visual analogue scale(VAS),Western Ontario and McMaster Universities osteoarthritis index(WOMAC)score,interleukin-1(IL-1)and tumor necrosis factor-α(TNF-α)levels were recorded in the two groups,and the therapeutic effects were compared between the two groups.Results The VAS,WOMAC scores,IL-1 and TNF-αlevels of the two groups after treatment were lower than those before treatment,and the VAS,WOMAC scores,IL-1 and TNF-αlevels of the treatment group after treatment were lower than those of the control group,and the differences were statistically significant(P<0.05).The total effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Lingshu Kaihe turbid-toxin acupuncture combined with external use of traditional Chinese medicine is effective in the clinical treatment of knee osteoarthritis caused by cold-damp obstruction.It can relieve the pain of patients to a certain extent,and has the characteristics of simple and cheap,which is worthy of research and promotion.