宫颈癌肉瘤一例并文献复习

Cervical Carcinosarcoma:A Case Report and Literature Review

宫颈癌肉瘤(cervical carcinosarcoma)是一种由恶性的上皮组织和间质成分组成的恶性肿瘤,患者通常以不规则阴道出血、流液就诊,其病因及发病机制尚不明确,临床上十分罕见,因此容易造成误诊和漏诊。现报告1例42岁宫颈癌肉瘤的病例资料,患者因接触性出血伴下腹痛收入院,盆腔磁共振成像示宫颈部体积明显增大,初步诊断为宫颈恶性肿瘤,遂行根治性全子宫切除+盆腔淋巴结切除+大网膜切除术,术后病理学明确诊断为宫颈癌肉瘤Ⅱb期。截至2024年3月2日,患者已行3次化疗,暂未发现复发及转移。宫颈癌肉瘤恶性程度高,临床表现无特异性,确诊主要依靠病理学检查和免疫组织化学检查,因此早识别、早治疗对改善患者的预后至关重要。

Cervical carcinosarcoma is a malignant tumor composed of malignant epithelial tissue and stromal components.Patients typically present with irregular vaginal bleeding and discharge.The etiology and pathogenesis of this condition remain unclear,and it is clinically very rare,making misdiagnosis and missed diagnosis common.This report presents a case of 42-year-old woman with cervical carcinosarcoma.The patient was admitted to the hospital due to contact bleeding accompanied by lower abdominal pain.Pelvic magnetic resonance imaging revealed a significant enlargement of the cervical region,with an initial diagnosis of cervical tumor.The patient subsequently underwent radical hysterectomy,pelvic lymphadenectomy,and omentectomy.Postoperative pathology confirmed the diagnosis of cervical carcinosarcoma,stageⅡb.As of March 2,2024,the patient had undergone three rounds of chemotherapy,with no evidence of recurrence or metastasis detected so far.Cervical carcinosarcoma is highly malignant with nonspecific clinical manifestations,and definitive diagnosis relies mainly on pathological and immunohistochemical examinations.Therefore,early recognition and treatment are crucial for improving patient prognosis.