顾步汤联合腔内成形术对下肢动脉硬化闭塞症患者双足震动感觉阈值及微循环的影响

Effects of Gubu decoction combined with intraluminal reconstruction on bipedal vibration sensation threshold and microcirculation in patients with lower extremity arteriosclerotic occlusive disease

[目的]探究顾步汤联合腔内成形术对下肢动脉硬化闭塞症(LEAOD)患者双足震动感觉阈值及微循环的影响。[方法]将152例2021年4月—2023年4月于丽水市中心医院进行LEAOD治疗的患者,通过随机数字表法分为观察组(腔内成形术+顾步汤,76例)和对照组(腔内成形术,76例),对两组患者的中医证候积分、临床疗效、微循环指标和双足震动感觉阈值做对比。[结果]两组肢体疼痛、肢体麻木、间歇性跛行、肢体怕冷等中医证候积分在治疗后均下降,且观察组下降幅度更明显(P<0.05);观察组临床疗效(96.05%)显著高于对照组(84.21%)(P<0.05);两组患者治疗后流态积分、管襻积分、襻周积分均下降,襻顶血管直径均增加,且观察组各项指标变化更明显(P<0.05);治疗后两组双足震动感觉阈值均下降,且观察组变化更为显著(P<0.05)。[结论]顾步汤联合腔内成形术能够有效降低LEAOD患者的双足震动感觉阈值,改善患肢微循环。

Aim To investigate the effects of Gubu decoction combined with intraluminal reconstruction on bipedal vibration sensation threshold and microcirculation in patients with lower extremity arteriosclerotic occlusive disease(LEAOD).Methods A total of 152 patients who came to Lishui Gentral Hospital for LEAOD treatment from April 2021 to April 2023 were divided into the observation group(intraluminal reconstruction+Gubu decoction,76 cases)and the control group(intraluminal reconstruction,76 cases)by random number table method,and the traditional Chinese medicine(TCM)syndrome scores,clinical efficacy,microcirculation indicators and bifoot vibration sensation threshold of the two groups were compared.Results After treatment,the scores of TCM syndromes such as limb pain,limb numbness,intermittent claudication,and limb fear of cold decreased after treatment in both groups,and the decrease of observation group was more obvious(P<0.05).The clinical effect of observation group(96.05%)was significantly higher than that of control group(84.21%)(P<0.05).After treatment,the flow state integral,tube loop integral and periloop integral decreased,and the apical vessel diameter increased in both groups,and the changes of various indexes in the observation group were more significant(P<0.05).After treatment,the threshold of sensation in both groups decreased,and the observation group was significantly lower(P<0.05).Conclusion Gubu decoction combined with intraluminal reconstruction can effectively reduce the foot sensation threshold and improve the microcirculation of affected limbs in LEAOD patients.