前列腺增生TURP术后腺体再次增生的影响因素分析

Analysis of influencing factors of glandular rehyperplasia after TURP operation

目的:分析前列腺增生经尿道前列腺电切术(TURP)术后腺体再次增生的影响因素。方法:纳入2022年1月~2024年4月期间我院收治的29例前列腺增生TURP术后腺体再次增生患者(复发组)和36例前列腺增生TURP术后腺体未再次增生患者(未复发组),进行回顾性分析。收集两组患者一般资料进行单因素比较,将有显著性差异的单因素进行logistic回归分析,分析影响前列腺增生患者TURP术后再次增生的独立危险因素。结果:2组患者手术时年龄、前列腺突入膀胱、白细胞、血中性分叶核粒细胞百分率、手术时间、住院时间、尿潴留、膀胱结石比较无明显差异(P>0.05);发病年龄、2型糖尿病(T2DM)、前列腺前后径、手术切除前列腺组织重量、残留腺体、残余尿量、血尿酸、血肌酐、尿蛋白比较存在显著差异(P<0.05)。经logistic回归分析,发病年龄、T2DM、前列腺前后径、残留腺体、血尿酸、血肌酐、尿蛋白为影响前列腺增生患者TURP术后腺体再次增生的独立危险因素(P<0.05)。结论:发病年龄、T2DM、前列腺前后径、残留腺体、血尿酸、血肌酐、尿蛋白为影响前列腺增生患者TURP术后腺体再次增生的危险因素,临床需对此类患者高度重视,及时采取对应措施干预降低其复发风险。

Objective:To analyze the factors influencing glandular rehyperplasia after transurethral resection of prostate(TURP).Methods:From January 2022 to April 2024,29 patients with glandular re-proliferation after TURP for BPH(recurrence group)and 36 patients without glandular re-proliferation after TURP for BPH(non-recurrence group)were included in the hospital for retrospective analysis.The general data of the two groups of patients were collected for univariate comparison,and univariate factors with significant differences were analyzed by logistic regression analysis to analyze the independent risk factors affecting the recurrence of re-proliferation after TURP in patients with BPH.Results:There were no significant differences between groups in terms of age at the time of surgery,prostate protruding into the bladder,white blood cell,percentage of blood neutrophils,surgical time,hospitalization time,urinary retention and bladder stones(P>0.05).There were significant differences in age of onset,type 2 diabetes mellitus(T2DM),prostate anteroposterior diameter,weight of resected prostate tissue,residual gland,residual urine volume,serum uric acid,serum creatinine and urinary protein(P<0.05).Logistic regression analysis found that age of onset,T2DM,prostate anteroposterior diameter,residual gland,serum uric acid,serum creatinine and urinary protein were independent risk factors for glandular re-proliferation after TURP in patients with BPH(P<0.05).Conclusion:The age of onset,T2DM,prostate anteroposterior diameter,residual gland,serum uric acid,serum creatinine and urinary protein are the risk factors affecting the glandular re-proliferation after TURP in patients with BPH.It is necessary to attach great importance to such patients and take corresponding measures in time to reduce the risk of recurrence.