老年患者发生肌少症的多因素Logistic回归分析

Multivariate Logistic regression analysis of sarcopenia in elderly patients

目的分析老年患者发生肌少症的影响因素。方法选取2021年11月至2023年4月在上饶市人民医院住院的327例老年患者作为研究对象,根据诊断结果分为肌少症组(n=80)与非肌少症组(n=247)。收集两组人口学信息、病史及日常生活活动能力评定量表(BI)、营养风险筛查(NRS)和衰弱筛查量表(FRAI),采用多因素Logistic回归分析老年患者发生肌少症的危险因素。结果单因素分析显示,年龄≥80岁、体重指数(BMI)过低、丧偶/离婚/未婚、合并冠心病、合并骨质疏松症、运动较少、日常生活能力障碍、体质衰弱、有营养风险与老年患者发生肌少症相关(P<0.05)。多因素Logistic回归分析结果显示,年龄≥80岁、BMI过低、合并骨质疏松症、日常生活活动能力障碍、体质衰弱均为老年患者发生肌少症的独立危险因素(P<0.05)。结论年龄≥80岁、BMI过低、合并骨质疏松症、日常生活活动能力障碍、体质衰弱的老年患者为肌少症重点监控人群,医护人员需结合老年患者实际病情采取相应的干预措施,减少肌少症发生风险。

Objective To analyze the influencing factors of sarcopenia in elderly patients.Methods 327 elderly patients admitted to Shangrao People's Hospital from November 2021 to April 2023 were selected as the research subjects,they were divided into the sarcopenia group(n=80)and non-sarcopenia group(n=247)according to diagnostic results.The demographic information,medical history,barthel index(BI),nutritional risk screening scale(NRS)and frailty screening scale(FRAI)of the two groups were collected,the risk factors of sarcopenia in elderly patients were analyzed by multivariate Logistic regression analysis.Results Univariate analysis showed that age≥80 years,too low BMI,widowed/divorced/unmarried status,coronary heart disease,osteoporosis,little exercise,disability of daily living,asthenia and nutritional risk were correlated with sarcopenia(P<0.05).The results of multivariate Logistic regression analysis showed that age≥80 years,too low BMI,osteoporosis,disability of daily living and asthenia were independent risk factors of sarcopenia(P<0.05).Conclusion Close attentions should be payed to elderly patients with age≥80 years,too low BMI,osteoporosis,disability of daily living and asthenia,medical staffs should take appropriate intervention measures according to actual conditions of elderly patients to reduce sarcopenia risk.