高血压的药物治疗

Pharmacological treatment for hypertension

高血压是全球常见的慢性疾病之一,可显著增加心力衰竭、心肌梗死、卒中等心血管事件发生风险。生活方式干预虽然可在一定程度上降低患者血压,减少总体心血管风险,但大部分高血压患者需要在生活方式干预基础上予以降压药物治疗才能实现血压达标。如今,高血压药物治疗领域的理念和手段均有了显著进步,在五大类经典降压药物基础上,发展出了单片复方制剂和许多新型降压药物。文章将针对高血压药物治疗方面的现状和进展进行综述。

Hypertension is one of the most common chronic diseases worldwide,significantly increasing the risk of cardiovascular events such as heart failure,myocardial infarction,and stroke.While lifestyle interventions can reduce blood pressure to some extent and reduce overall cardiovascular risk,most hypertension patients require additional antihypertensive medication to achieve optimal blood pressure control.Today,the field of pharmacological treatment for hypertension has seen significant progress in both concepts and methods.In addition to the five major classes of classic antihypertensive drugs,single-pill compound and many new antihypertensive agents have been developed.This article will provide a brief review of the current status and progress in the pharmacological treatment for hypertension.