期刊文献+

人造卵巢的构建技术及应用研究进展

Advances in the construction technology and application of artificial ovaries
下载PDF
导出
摘要 卵巢功能失调导致的雌激素和孕激素分泌减少会引起更年期综合征、骨质疏松、心血管疾病和阿尔茨海默症等疾病的发生。同时,化疗、放疗会造成女性癌症患者卵巢早衰而丧失生育能力。为了更好地模拟卵巢生理结构和功能、优化现有生育力保存技术,改善老龄化女性人口的生活质量,人造卵巢一直以来都是生殖和再生医学领域研究的热点。 Reduced estrogen and progesterone secretion due to ovarian dysfunction can cause menopausal syndrome,osteoporosis,cardiovascular disease and Alzheimer's disease.Meanwhile,chemotherapy and radiotherapy can cause premature ovarian failure and loss of fertility in female cancer patients.In order to better mimic the physiological structure and function of the ovary,optimize existing fertility preservation techniques,and improve the quality of life of the aging female population,artificial ovaries have long been a hot topic of research in the field of reproductive and regenerative medicine.
作者 李佳曌 Li Jiazhao(Scientific Research Department,Wannan Medicial College,Wuhu Anhui,241002,China)
出处 《中外女性健康研究》 2024年第10期55-58,共4页 Women's Health Research
基金 芜湖市科技计划项目,项目编号:2021cg34。
关键词 人造卵巢 生育力保存 癌症患者 Artificial ovaries Fertility preservation Cancer patients
  • 相关文献

参考文献2

二级参考文献15

  • 1Morgan S, Anderson RA, Gourley C,et al. How do chemothera?peutic agents damage the ovary ?[1). Hum Reprod Update, 2012, 18: 525-535.
  • 2Siegel R, MaJ, Zou Z,et al. Cancer statistics, 2014[1). CA CancerJ Clin, 2014,64:9-29.
  • 3National Bureau of Statistics of the People's Republic of China. The 6th National Population Census.2010.
  • 4De Vos M, SmitzJ, Woodruff TK. Fertility preservation in wom?en with cancer[J]. Lancet, 2014,384: l302-l31O.
  • 5Tournaye H, Dohle GR, Barratt CLR. Fertility preservation in men with cancer[J]. Lancet,2014,84:1295-l301.
  • 6Cobo A, Diaz C. Clinical application of oocyte vitrification: a sys?tematic review and meta- analysis of randomized controlled tri?als[1). Fertil Steril, 2011,96: 277-285.
  • 7Silber S, Kagawa N, Kuwayama M,et al. Duration of fertility after fresh and frozen ovary transplantation[Jl Fertil Steril, 2010,94: 2191-2196.
  • 8Le Ray C, Scherier S, Anselem O,et al. Association between oo?cyte donation and maternal and perinatal outcomes in women aged 43 years or older[1). Hum Reprod, 2012,27:896-901.
  • 9Ahn RW, Barrett SL, Raja MR,et al. Nano-encapsulation of arse?nic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vi?vo[J]. PloS one, 2013, 8:e58491.
  • 10Morita Y, Perez GI, Paris F,et al. Oocyte apoptosis is sup?pressed by disruption of the acid sphingomyelinase gene or hy sphingosine+l+ phosphato therapy[1). Nat Med, 2000,6: 1109- 1114.

共引文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部