参松养心胶囊联合美托洛尔缓释片治疗老年冠心病心律失常患者的临床效果

Clinical effect of Shensong Yangxin capsules combined with metoprolol sustained-release tablets in the treatment of elderly patients with coronary heart disease and arrhythmia

目的研究参松养心胶囊联合美托洛尔缓释片治疗老年冠心病心律失常患者的临床效果。方法回顾性选取2020年6月至2021年6月我院收治的96例老年冠心病心律失常患者作为研究对象,依据治疗方法不同将其分为联合治疗组(美托洛尔缓释片联合参松养心胶囊治疗)和单独治疗组(美托洛尔缓释片治疗),各48例。比较两组的治疗效果。结果联合治疗组的治疗总有效率高于单独治疗组(P<0.05)。治疗后,联合治疗组的心功能分级优于单独治疗组(P<0.05)。治疗后,联合治疗组的心排出量、心脏指数、射血分数均高于单独治疗组(P<0.05)。联合治疗组的室性期前收缩、房性期前收缩、交界性期前收缩、短阵心房颤动发生次数均少于单独治疗组(P<0.05)。治疗后,联合治疗组的缺血发生次数、缺血总负荷低于单独治疗组,缺血持续时间短于单独治疗组(P<0.05)。联合治疗组的不良反应总发生率低于单独治疗组(P<0.05)。结论参松养心胶囊联合美托洛尔缓释片治疗老年冠心病心律失常效果显著,可减少其心律失常发作频率,改善心功能。

Objective To study the clinical effect of Shensong Yangxin capsules combined with metoprolol sustained-release tablets in the treatment of elderly patients with coronary heart disease and arrhythmia.Methods A total of 96 elderly patients with coronary heart disease and arrhythmia admitted in our hospital from June 2020 to June 2021 were retrospectively selected as the research objects.According to different treatment methods,the patients were divided into combined treatment group(treated with metoprolol sustained-release tablets combined with Shensong Yangxin capsules)and single treatment group(treated with metoprolol sustained-release tablets),with 48 cases in each group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment of the combined treatment group was higher than that of the single treatment group(P<0.05).After treatment,the cardiac function classification of the combined treatment group was better than that of the single treatment group(P<0.05).After treatment,the cardiac output,cardiac index and ejection fraction of the combined treatment group were higher than those of the single treatment group(P<0.05).The incidences of ventricular premature contraction,atrial premature contraction,junctional premature contraction and short atrial fibrillation in the combined treatment group were less than those in the single treatment group(P<0.05).After treatment,the number of ischemic occurrence and total ischemic load in the combined treatment group were lower than those in the single treatment group,and the duration of ischemia was shorter than that in the single treatment group(P<0.05).The total incidence of adverse reactions in the combined treatment group was lower than that in the single treatment group(P<0.05).Conclusion Shensong Yangxin capsules combined with metoprolol sustained-release tablets has a significant effect on elderly patients with coronary heart disease and arrhythmia,which can reduce the incidence of arrhythmia and improve cardiac function.