静脉溶栓治疗210例急性脑梗死临床分析

Clinical Analysis of Intravenous Thrombolysis Therapy in 210 Patients with Acute Cerebral Infarction

为探讨静脉溶栓治疗急性脑梗死的疗效,将内蒙古民族大学附属医院神经内科2016年5月—2020年11月收治的急性脑梗死患者380例随机分为2组,治疗组210例采用尿激酶或阿替普酶静脉溶栓治疗,对照组170例采用常规治疗,并进行2组对照分析。结果显示:治疗组显效58例,有效131例,无效21例,总有效率90.0%;对照组显效9例,有效119例,无效42例,总有效率75.3%;2组疗效比较P<0.05。治疗组并发颅内出血6例(2.9%),死亡4例(1.9%);对照组并发颅内出血2例(1.2%),死亡3例(1.8%);2组并发颅内出血率及死亡率比较P>0.05。可见急性脑梗死患者应用尿激酶或阿替普酶进行静脉溶栓治疗疗效显著,安全可靠。

To investigate the efficacy of intravenous thrombolysis in the treatment of acute cerebral infarction,380 patients with acute cerebral infarction admitted to the Department of Neurology,Affiliated Hospital of Inner Mongolia Minzu University from May 2016 to November 2020 were randomly divided into two groups,210 patients in the treatment group received intravenous thrombolytic therapy of urokinase or alteplase,and 170 patients in the control group received conventional treatment,the curative effect of the two groups were compared and analyzed.The results showed:in the treatment group,58 cases were noticeably effective,131 cases were effective,21 cases were ineffective,and the total effective rate was 90.0%.In the control group,9 cases were noticeably effective,119 cases were effective,42 cases were ineffective,and the total effective rate was 75.3%.The curative effect of the two groups was compared,and P<0.05.In the treatment group,6 cases(2.9%)were complicated with intracranial hem⁃orrhage and 4 cases(1.9%)died.In the control group,2 cases(1.2%)were complicated with intracranial hemor⁃rhage and 3 cases(1.8%)died.The complication rate of intracranial hemorrhage and mortality rate of the two groups were compared,and P>0.05.It can be seen that intravenous thrombolytic therapy with urokinase or al⁃teplase in patients with acute cerebral infarction is effective,safe and reliable.