清热化湿方治疗大肠息肉切除术后临床观察

Efficacy observation of Qingre Huashi formula on post-resection colorectal polyps

目的:观察清热化湿方预防肠道湿热型大肠息肉内镜切除术后复发的临床效果。方法:将符合纳入标准的内镜下行大肠息肉切除术患者60例,随机分为两组各30例。术后对照组不予药物干预,治疗组予清热化湿方口服,疗程为8周。结果:治疗组总有效率90.00%,对照组总有效率73.33%,两组比较差异有统计学意义(P﹤0.05);治疗组复发率23.33%,对照组复发率46.67%,两组比较差异无统计学意义(P=0.058);治疗后,两组患者中医症状积分较治疗前均降低(P﹤0.05),且治疗组降低程度更明显(P﹤0.05)。结论:清热化湿方治疗肠道湿热型大肠息肉切除术后患者疗效较好,可缓解患者腹痛等症状,降低复发率。

Objective:To observe the clinical efficacy of Qingre Huashi formula on recurrence of colorectal polyps with syndrome of intestinal damp-heat after endoscopic resection.Methods:60 cases of eligible patients with colorectal polyps after endoscopic resection were randomly divided into two groups,30 cases in each group.The control group was not given drug intervention after operation,while the treatment group was treated with oral Qingre Huashi formula for 8 weeks.Results:The total effective rate was 90.00%in the treatment group and 73.33%in the control group,and the comparative difference between two groups was statistically significant(P﹤0.05).The recurrence rate of treatment group was 23.33%,while that of control group was 46.67%,and the comparative difference between two groups was unsignificant(P=0.058).TCM symptom scores were decreased in both groups after treatment compared with before treatment(P﹤0.05),and the decreased degree of treatment group was more obvious(P﹤0.05).Conclusion:The clinical efficacy of Qingre Huashi formula on post-resection colorectal polyps with syndrome of intestinal damp-heat is better,which can relieve symptoms of patients such as abdominal pain,etc.and reduce the recurrence rate.