自身免疫性肝病发病机制的研究进展

Research progress on pathogenesis of autoimmune liver diseases

自身免疫性肝病(AILD)是一组病因不明,免疫介导的慢性肝脏损伤性疾病。该类疾病的发病机制目前尚不明确,临床表现具有非特异性,较难确诊,对人类生命健康长期存在严重威胁。现将AILD发病机制的研究进展综述如下,以期为AILD的临床诊疗提供新靶点和有力证据。

Autoimmune liver diseases(AILD) represent a group of chronic,immune-mediated liver injuries with unknown etiology.The pathogenesis of these diseases remains elusive,and their clinical manifestations are non-specific,posing significant challenges for accurate diagnosis and long-term threats to human health.Therefore,the pathogenesis of AILD was reviewed,aiming to provide novel targets and robust evidence for clinical diagnosis and treatment of AILD.