超声引导下神经阻滞术治疗脊神经卡压综合征的效果分析

Effect analysis of ultrasound-guided nerve block in the treatment of spinal nerve entrapment syndrome

目的探讨脊神经卡压综合征患者经超声引导下进行神经阻滞治疗的临床效果。方法选取2021年1月至2022年12月景德镇市第三人民医院收治120例脊神经卡压综合征患者作为研究对象,采用随机数字表法分为对照组与实验组,每组60例。对照组采用常规药物治疗,实验组在对照组的基础上采用超声引导下神经阻滞术治疗。比较两组疼痛控制总有效率,治疗前后视觉模拟评分法(visual analog scale,VAS)评分、颈部残障指数(neck disability index,NDI)、Oswestry功能障碍指数(Oswestry disability index,ODI),治疗前后血清相关指标[皮质醇(cortisol,Cor)、肾上腺素(epinephrine,E)、白细胞介素-6(interleukin-6,IL-6)]及不良反应发生情况。结果实验组疼痛控制总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组VAS评分、NDI、ODI均低于治疗前,JOA评分高于治疗前,且实验组VAS评分、NDI、ODI均低于对照组,JOA评分高于对照组,差异有统计学意义(P<0.05)。治疗后,两组血清Cor、E、IL-6水平均低于治疗前,且实验组低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论经超声引导下进行神经阻滞治疗脊神经卡压综合征患者,能显著提高疼痛控制效率,改善腰椎功能,降低残障风险,可能与Cor、E、IL-6表达下调有关,且安全性较高,值得临床推广应用。

Objective To explore the clinical effect of ultrasound-guided nerve block therapy in patients with spinal nerve entrapment syndrome.Methods A total of 120 patients with spinal nerve compression syndrome admitted to Jingdezhen Third People's Hospital from January 2021 to De-cember 2022 were selected as the study subjects,and they were divided into the control group and the experimental group according to the random number table method,with 60 cases in each group.The control group was treated with conventional drugs,and the experimental group was treated with ultrasound-guided nerve block based on the control group.The total effective rate of pain control,visual analogue scale(VAS)score,neck dis-ability index(NDI),Oswestry Disability Index(ODI),serum related indexes(cortisol[Cor],epinephrine[E],interleukin-6[IL-6])before and after treatment and adverse reactions were compared between the two groups.Results The total effective rate of pain control in the experimental group was higher than that in the control group,the difference was statistically significant(P<0.05).After treatment,the VAS scores,NDI and ODI of the two groups were lower than before treatment,JOA scores was higher than before treatment,and VAS scores,NDI and ODI in the experimental group were lower than those in the control group,JOA scores was higher than that in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of serum Cor,E and IL-6 of the two groups were lower than before treatment,and the experimental group was lower than the control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse re-actions between the two groups.Conclusion Ultrasound-guided nerve block therapy for patients with spinal nerve entrapment syndrome can signifi-cantly improve the efficiency of pain control,improve lumbar function and reduce the risk of disability,which may be related to the down-regulation of Cor,E and IL-6 expression,which is safe,and worthy of clinical promotion and application.