MicroRNAs(miRs)、良性前列腺增生、慢性前列腺炎的关系

Relationship of miRNA,Benign Prostatic Hyperplasia and Chronic Prostatitis

慢性前列腺炎(Chronic nonbacterial prostatitis, CNP)与良性前列腺增生(Benign prostatic hyperplasia, BPH)是男性常见疾病,因此,对于前列腺发病机制的研究已经成为学术界的研究热点。miRNA作为一类非编码RNA广泛存在于生物体中,并且在许多人类疾病中的调节作用已经被观察到,然而迄今为止,miRNA参与BPH与前列腺炎的具体机制尚不明确,它们在BPH与前列腺炎中的作用尚未得到充分探讨。因此,未来对miRNA参与BPH和前列腺炎中发病机制的进一步研究可能对于了解疾病和开发新的潜在治疗方法提供重要线索。

Chronic nonbacterial prostatitis(CNP)and benign prostatic hyperplasia(BPH)are common diseases in men,therefore,the study of prostate disease pathogenesis has become a hot research topic in the academic world.MiRNAs,as a class of non-coding RNAs,are widely present in living organisms,and their regulatory roles in many human diseases have been observed;however,to date,the involvement of miRNAs in BPH and prostatitis is unclear and their specific mechanisms have not been fully explored in BPH and prostatitis.Therefore,further future studies on the involvement of miRNAs in the pathogenesis of BPH and prostatitis may provide important clues for understanding the disease and developing new potential therapeutic approaches.