超微血流成像技术定量评估正常中晚孕胎盘血流的临床分析

Clinical Analysis of Placental Blood Flow Assessment Using by Superb Microvascular Imaging in Normal Second and Third Trimester Pregnancies

目的:研究超微血流成像技术定量评价中晚孕孕妇胎盘血流灌注情况的价值。方法:选取2022年3月-2023年12月间在我院产科正常健康产检的产妇88例为研究对象,孕周为22~40周,均应用彩色多普勒超声进行超微血流成像检查,根据孕妇的孕周不同分成四组:A组(孕22~28周,n=23)、B组(孕28+~32周,n=24)、C组(孕32+~36周,n=21)、D组(孕36+~40周,n=20),对比四组孕妇超微血流成像的声像图特征以及相关参数。结果:A组孕妇的胎盘内血管主要表现为点状分布,B组、C组、D组孕妇的胎盘内血管呈树枝状分布,且血管变粗,分支变多。随着孕周的增加,孕妇胎盘的血管化指数(VI)、血流指数(FI)、血管化-血流指数(VFI)均明显提高(P<0.05)。结论:超微血流成像技术在中晚孕孕妇中应用能准确评估胎盘的血流灌注情况,为产前筛查孕妇有无胎盘灌注不足相关疾病提供可靠的诊断依据。

Objective:To evaluate the value of quantitative assessment of placental blood perfusion in normal second and third trimester pregnancies using superb microvascular imaging(SMI)technology.Methods:88 healthy pregnant women who underwent routine antenatal care in our hospital between March 2022 and December 2023,with gestational ages ranging from 22 to 40 weeks,were enrolled.All participants underwent SMI examination via color Doppler ultrasound.According to the gestational age of pregnant women,they were divided into four groups:Group A(22 to 28 weeks,n=23),Group B(28+to 32 weeks,n=24)and Group C(32+to 36 weeks,n=21)and Group D(36 weeks+to 40 weeks,n=20)of pregnant women.Results:The placental vessels in group A showed punctate distribution,while the placental vessels in group B,C and D were dendritic,with thickened blood vessels and more branches.With the increase of gestational age,the vascularization index(VI),flow index(FI),and vascularization-flow index(VFI)of pregnant placenta increased significantly(P<0.05).Conclusion:SMI technique is helpful to observe the situation of placental blood perfusion,VI,FI and VFI values can quantitatively evaluate placental blood perfusion,provide data for the diagnosis and prediction of placental insufficiency perfusion related diseases in obstetrics,and guide the treatment.