Novel biomarkers for hepatocellular carcinoma detection and treatment

Hepatocellular carcinoma(HCC)ranks as the sixth most prevalent malignant tumor globally and is the third leading cause of cancer-related mortality,with its incidence and mortality rates demonstrating a consistent annual increase(1).The primary reason for this occurrence lies in the insidious onset of the disease,leading to late-stage diagnosis in a majority of patients,resulting in limited treatment options and poor efficacy.Consequently,emphasis on prevention and early detection is imperative for enhancing the prognosis of HCC patients.Furthermore,the identification of biomarkers with heightened sensitivity and specificity holds particular significance(2).