Early cholecystectomy cannot be regarded as a mortality risk factor in moderate and severe acute biliary pancreatitis

We read with great interest the article by Di Martino et al.(1)on the timing of cholecystectomy after moderately severe and severe acute biliary pancreatitis(ABP).In this retrospective study,the authors analyzed data from the MANCTRA-1 database.Of 5,304 patients,3,696 met the inclusion criteria(cholecystectomy performed and stage of pancreatitis known)and were included in the analysis.The aim of this study was to assess the impact of early cholecystectomy(EC)on morbidity and mortality in ABP,particularly in moderately severe and severe forms according to the modified Atlanta classification(2).EC was defined as removal of the gallbladder within 14 days of admission,and was compared with delayed cholecystectomy(DC).