雄激素与糖皮质激素在沉积物中的协同与竞争吸附研究

Synergistic and Competitive Sorption of Androgens and Glucocorticoids in Freshwater Sediment

雄激素与糖皮质激素在环境中广泛存在,对人体和生态健康造成风险,然而人们对它们在沉积物中的吸附行为仍知之甚少。该文研究2种雄激素和2种糖皮质激素在沉积物中单独和两两共存时的吸附规律。结果表明:4种激素的吸附更符合准二级动力学,初始浓度升高可使平衡吸附量增加、除DEX外吸附速率常数变小。吸附等温线更符合Langmuir模型,雄激素的吸附容量比糖皮质激素小,最小为雄烯二酮70.04 mg/kg,最大为可的松322.3 mg/kg。在双吸附质体系中,雄烯二酮分别与甲睾酮、地塞米松共存时表现为协同效应,地塞米松分别与可的松、甲睾酮共存时表现为竞争吸附。该研究有助于完善对类固醇激素环境行为的认知,为准确评估其生态风险提供理论依据。

Androgens and glucocorticoids are prevalent in the environment,posing significant risks to human and ecological health.However,their sorption behaviors in sediments remain poorly understood.This study investigated the sorption characteristics of two androgens and two glucocorticoids,both individually and in binary mixtures,in freshwater sediment.The results showed that the sorption of these four steroids aligned more closely with pseudo-second order kinetics.Higher initial concentrations resulted in larger equilibrium sorption capacities and smaller sorption rate constants except DEX.The sorption isotherms were better described by the Langmuir model,with androgens exhibiting smaller adsorption capacities compared to glucocorticoids,ranging from a minimum of 70.04 mg/kg for androstenedione to a maximum of 322.3 mg/kg for cortisone.In binary adsorbate systems,the coexistence of androstenedione and methyltestosterone exhibited synergistic sorption,as did the coexistence of androstenedione and dexamethasone.Dexamethasone competed with either cortisone or methyltestosterone when they coexisted.This study enhances the understanding of the environmental fate of steroid hormone and provides theoretical support for accurately assessing their ecological risks.