髌下脂肪垫大小及信号强度与髌股关节结构损伤相关性的MRI研究

MRI Study on Correlation between Size and Signal Intensity of IPFP and Patellofemoral Joint Structural Damage

目的 探究髌下脂肪垫(IPFP)大小及信号强度与髌股关节结构损伤之间的关系。方法回顾性分析100例同时行膝关节X线和MRI检查受试者的临床和影像学资料,于矢状位PDWI-FS图像上测量IPFP厚度及最大横截面积(CSA),半定量评估IPFP信号强度,并对髌骨软骨缺损、骨赘及骨髓病变三种结构损伤进行评估,分析IPFP大小及信号强度与髌股关节结构损伤的相关性。进一步根据K-L分级(Kellgren-Lawrence grading)将研究对象分为ROA组和非ROA组,比较两组间IPFP的差异。结果IPFP厚度、最大CSA与髌骨软骨缺损、骨赘呈显著负相关(P<0.05),IPFP信号强度与髌骨软骨缺损、骨赘呈显著正相关(P<0.05),ROA组的IPFP厚度及最大CSA小于非ROA组,ROA组的IPFP信号强度高于非ROA组,差异有统计学意义(P<0.05)。结论IPFP大小及信号增高与髌股关节结构损伤存在相关性,可能是髌股骨关节炎发生和发展的潜在影响因素。

Objective To investigate the associations between size and signal intensity of Infra patellar fat pad(IPFP)and patellofemoral joint structu ral damage.Methods The clinical and imaging data of 100 su bjects who both underwent knee of X-ray and MRI were retrospectively collected and analyzed.The thickness and maximum cross-sectional area(CSA) of IPFP were measured on sagittal PDWI-FS sequence images,and the signal intensity of IPFP were evaluated semiquantitatively.MRI was used to assess patellar ca rtilage defects,osteophytes and bone marrow lesions,and their correlations with the IPFP size and signal intensity were analyzed.According to the K-L classification on X-ray films,the participants were further divided into ROA and non-ROA group to compare the differences of IPFP between them.Results The thickness and maximum CSA of IPFP were negatively correlated with patella r ca rtilages and osteophytes(P<0.05),the signal intensity of IPFP was positively associated with patellar cartilages and osteophytes(P<0.05).IPFP thickness and maximum CSA were smaller in the ROA group compared to the non-ROA group,IPFP signal intensity was higher in the ROA group compared to the non-ROA group,and the differences were statistically significant(P<0.05).Conclusion IPFP size and increased signal are associated with patellofemoral joint structural da mage,suggesting that IPFP may be the potential influencing factors for the development and progression of patellofemoral joint osteoarthritis.