良性阵发性位置性眩晕患者SRM-IV眩晕诊疗系统治疗后眩晕残障现状及相关影响因素研究

Prospective Cohort Study of Vertigo Disability and Related Influencing Factors in Patients with Benign Paroxysmal Positional Vertigo Treated with SRM-IV Vertigo Diagnosis and Treatment System

目的探讨良性阵发性位置性眩晕(BPPV)患者SRM-IV眩晕诊疗系统治疗后眩晕残障现状的影响因素。方法采用前瞻性队列研究,选取2022年4月至2023年4月于西宁市第一人民医院进行SRM-IV眩晕诊疗系统治疗的BPPV患者100例为研究对象,分析治疗后患者的眩晕残障现状及相关影响因素。结果与治疗前相比,BPPV患者治疗后眩晕残障程度量表(DHI)评分较低(68.36±13.14 vs 45.29±8.20)分。与治疗有效的BPPV患者相比,治疗无效的BPPV患者治疗后DHI评分较高(43.32±7.01 vs 67.89±14.01)分。单因素分析显示,≥60岁、病程≥3个月、有头部外伤史、有高血压、高血脂、高血糖、半规管轻瘫CP值≥20%、25羟维生素D3[25-(OH)-D3]<30μg/L、同型半胱氨酸(Hcy)≥13μmol/L、嵴帽型、雌二醇(E2)<100 pmol/L的BPPV患者SRM-IV眩晕诊疗系统治疗后DHI评分较高。多因素Logistics回归分析显示,年龄、病程、头部外伤史、高血压、高血脂、高血糖、半规管轻瘫CP值、25-(OH)-D3、Hcy、疾病类型、E2为影响BPPV患者SRM-IV眩晕诊疗系统治疗后眩晕残障现状的主要因素。结论BPPV患者经SRM-IV眩晕诊疗系统治疗后眩晕残障现状改善,合并症、病情严重程度、外伤史等均与眩晕残障现状相关。

Objective To investigate the status quo and the influencing factors of vertigo disability in patients with benign paroxysmal positional vertigo(BPPV)after treatment with SRM-IV vertigo diagnosis and treatment system.Methods A prospective cohort study was conducted.A total of 100 BPPV patients treated with SRM-IV vertigo diagnosis and treatment system in Xining First People's Hospital from April 2022 to April 2023 were selected as the study objects.Their clinical data were collected.The status quo of vertigo disability after treatment and the related influencing factors were analyzed.Results The score of Dizziness Handicap Inventor(DHI)in BPPV patients before treatment was higher than that after treatment(68.36±13.14 vs 45.29±8.20)(P<0.05).The DHI score after treatment in patients who showed significant improvement was lower than that in patients who did not respond to the treatment(43.32±7.01 vs 67.89±14.01)(P<0.05).Univariate analysis showed that BPPV patients≥60 years old,and with disease course≥3 months,history of head trauma,hypertension,hyperlipidemia,hyperglycemia,value of canal paresis(CP)≥20%,25 hydroxyvitamin D3[25-(OH)-D3]<30μg/L,homocysteine(Hcy)≥13μmol/L,crest cap type,estradiol(E2)<100 pmol/L had higher DHI scores after treatment with SRM-IV vertigo diagnosis and treatment system.Multivariate Logistic regression analysis showed that age,course of disease,history of head trauma,hypertension,hyperlipidemia,hyperglycemia,CP value,25-(OH)-D3,Hcy,disease type and E2 were the main factors affecting the status of vertigo disability in BPPV patients after treatment with the SRM-IV vertigo diagnosis and treatment system.Conclusion The status quo of vertigo disability in BPPV patients is improved after treatment with the SRM-IV vertigo diagnosis and treatment system.And the comorbidities,severity of the disease,and history of trauma are all related to the status quo of vertigo disability.