The Rising Burden of Hepatocellular Carcinoma: Is the Gender Gap Narrowing?

Dear Editors,The landscape of hepatocellular carcinoma(HCC)is continuously evolving.Recent global trends indicate a significant shift in the epidemiology of HCC from viral-related to non-viral-related etiologies.Metabolic-associated fatty liver disease has emerged as the fastest-growing contributor to HCC in recent years,due to the increased prevalence of obesity and metabolic risk factors.