摘要
Fibroblasts serve as the primary source of extracellular matrix and play a crucial role in the remodeling of fibrotic tissue.Beyond their structural functions,fibroblasts also influence inflammatory processes and angiogenesis through the release of various mediators,potentially contributing to the inflammatory and vasculopathic aspects of systemic sclerosis(SSc).A recent study published in J Invest Dermatol delves into the varied functionalities of fibroblast populations and their clinical implications.
