基于SPR的重金属离子检测技术研究进展

Research progress on SPR-based heavy metal ion detection technology

重金属离子浓度的检测对于人体健康和环境科学等领域具有重要意义。与其它离子检测方法相比,表面等离子体共振(surface plasmon resonance,SPR)技术具有无标记,灵敏度高和检测限低等优点,为重金属离子监测领域带来了新的可能性。本文综述了SPR传感技术在重金属离子检测中的应用及其技术进展。首先介绍了SPR传感的技术原理;然后在传感材料的选择以及表面修饰等方面,针对铅、汞等有害重金属离子,重点阐述了对灵敏度、线性动态范围和特异性等指标的改进;最后介绍了SPR成像传感技术在检测速度、灵敏度等方面取得的重大进展,展望了SPR技术的发展前景。

The detection of ion concentration is of great significance in the fields of human health and environmental science.Compared with other ion detection methods,surface plasmon resonance(SPR)technology has the advantages of label-free detection,high sensitivity,and low detection limits,which brings new possibilities to the field of heavy metal ion monitoring.This article reviews the application and technical advances of SPR sensing technology in heavy metal ion detection.Firstly,this paper introduces the technical principles of SPR sensing.Then the paper focuses on the selection of sensing materials and surface modification,it emphasizes improvements in indicators such as sensitivity,linear dynamic range,specially for harmful heavy metal ions such as Pb^(2+)and Hg^(2+).Finally,the significant progress in terms of detection speed,sensitivity,etc.is introduced,and the development prospects of SPR technology is discussed.