腹腔镜腹膜前间隙无张力修补术治疗老年复发腹股沟疝患者的有效性及安全性

Efficacy and safety of laparoscopic preperitoneal space tension-free repair in the treatment of elderly patients with recurrent inguinal hernia

目的分析腹腔镜腹膜前间隙无张力修补术治疗老年复发腹股沟疝患者的有效性及安全性。方法选取2020年1月至2022年12月收治的100例老年复发腹股沟疝患者为研究对象,将其随机分为常规组(50例,充填式无张力疝修补术治疗)和观察组(50例,腹腔镜腹膜前间隙无张力修补术治疗)。比较两组的治疗效果。结果观察组的手术总有效率显著高于常规组,差异具有统计学意义(P<0.05)。观察组的手术时长、术中出血量、卧床时长及住院时长优于常规组,差异具有统计学意义(P<0.05)。观察组的并发症总发生率、镇痛药物使用率及1年内再复发率低于常规组,差异具有统计学意义(P<0.05)。术后,观察组的β-内啡肽(β-EP)、神经肽Y(NPY)、前列腺素E_(2)(PGE_(2))、细胞间黏附分子-1(ICAM-1)、髓过氧化物酶(MPO)及皮质醇(Cor)水平低于常规组,差异具有统计学意义(P<0.05)。结论腹腔镜腹膜前间隙无张力修补术治疗老年复发腹股沟疝患者的效果理想。

Objective To analyze the efficacy and safety of laparoscopic preperitoneal space tension-free repair in the treatment of elderly patients with recurrent inguinal hernia.Methods A total of 100 elderly patients with recurrent inguinal hernia admitted from January 2020 to December 2022 were selected as the study objects and randomly divided into conventional group(50 cases,filling tension-free hernia repair)and observation group(50 cases,laparoscopic preperitoneal space tension-free repair).The therapeutic effects of the two groups were compared.Results The total effective rate of operation in the observation group was significantly higher than that in the conventional group,and the difference was statistically significant(P<0.05).The operation time,intraoperative blood loss,bed time and hospitalization time of the observation group were better than those of the conventional group,and the differences were statistically significant(P<0.05).The total incidence of complications,the use rate of analgesic drugs and the recurrence rate within 1 year in the observation group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).After surgery,the levels ofβ-endorphin(β-EP),neuropeptide Y(NPY),prostaglandin E_(2)(PGE_(2)),intercellular cell adhesion molecule-1(ICAM-1),myeloperoxidase(MPO)and cortisol(Cor)in the observation group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).Conclusion The laparoscopic preperitoneal space tension-free repair in the treatment of elderly patients with recurrent inguinal hernia has an ideal effect.