PET/CT预测肝细胞癌肝移植术后复发的研究进展

Research progress in prediction of hepatocellular carcinoma recurrence after liver transplantation using PET/CT

随着肝移植技术的日益成熟及术后管理水平的提高,肝移植已成为治疗肝细胞癌(HCC)的重要手段之一。术后复发是导致治疗失败的主要原因。因此,准确预测HCC肝移植患者术后复发风险具有重要的临床意义。PET/CT能够从分子水平反映细胞代谢及靶器官功能变化,其肿瘤代谢负荷参数已被纳入肝移植术后评估体系,并具有较好的预后评估价值。该文对PET/CT预测HCC患者肝移植术后复发的研究进行综述。

With the increasing maturity of liver transplantation technology and the improvement of postoperative management,liver transplantation has become one of the important means for treating hepatocellular carcinoma(HCC).However,the postoperative recurrence is the main reason for treatment failure.Therefore,it is of great clinical significance to accurately predict the risk of postoperative recurrence in patients undergoing liver transplantation for HCC.PET/CT can reflect cellular metabolism and function changes in target organ at the molecular level.The tumor metabolic burden parameters of PET/CT have been included in the post-transplant evaluation system for liver transplantation and have good prognostic value.This article provides a review of prediction of HCC recurrence after liver transplantation using PET/CT.