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功能性水凝胶伤口敷料的辐射制备及其研究进展

Radiation preparation and research progress of functional hydrogel wound dressings
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摘要 水凝胶伤口敷料是一种新型的医用材料,具有止血抗菌、缩短伤口愈合进程、减轻患者伤口疼痛等作用。在水凝胶伤口敷料的制备方法中,辐射技术是不可或缺的手段之一,与其他制备水凝胶的方法相比,辐射法无需额外添加交联剂,操作简单,无污染。此外,通过控制辐射吸收剂量和条件,可以确保产品的稳定性和一致性。利用辐照技术制备水凝胶伤口敷料可以一步实现产品的制备和灭菌,降低生产成本,同时也确保了产品的安全性。本文主要总结了辐射技术制备水凝胶伤口敷料的分类、特点及其研究进展。同时,总结了水凝胶伤口敷料的应用,对未来水凝胶伤口敷料的发展以及更好地运用于临床进行展望。 Wound hydrogel dressings are a novel type of medical material known for their hemostatic and antibacterial effects,which expedite wound healing and alleviate patient discomfort.Radiation technology plays an indispensable role in their preparation.Unlike other methods,radiation does not require additional crosslinking agents,simplifying the process and minimizing pollution.Moreover,product stability and consistency can be ensured by controlling absorbed radiation dose and conditions.Using radiation technology for hydrogel dressing preparation integrates sterilization into production,reducing costs and enhancing safety.This review categorizes,outlines characteristics,and surveys recent advances in radiation-prepared hydrogel wound dressings.Additionally,it summarizes their applications and forecasts their future development and expanded clinical utilization.
作者 刘坤 唐冬旭 付娌丽 王智俊 陈黄琴 李月生 LIU Kun;TANG Dongxu;FU Lili;WANG Zhijun;CHEN Huangqin;LI Yuesheng(School of Pharmacy,Hubei University of Science and Technology,Xianning 437100,China;School of Stomatology and Optometry,Hubei University of Science and Technology,Xianning 437100,China;Hubei Key Labortory of Radiation Chemistry and Functional Materials,Hubei University of Science and Technology,Xianning 437100,China;Hubei Smart Healthcare Industry Technology Research Institute,Hubei University of Science and Technology,Xianning 437100,China)
出处 《辐射研究与辐射工艺学报》 CAS CSCD 2024年第5期1-12,共12页 Journal of Radiation Research and Radiation Processing
基金 湖北省科技厅科技重点研发计划(2022BCE026) 湖北省高等学校优秀中青年科技创新团队项目(T2020022) 咸宁市科技研究与开发(高新类研发重点专项)项目(2021GXYF021) 湖北科技学院科学发展基金(2020TD01、2022FH09)资助。
关键词 辐射 水凝胶 伤口敷料 抗菌 止血 Radiation Hydrogel Wound dressing Antibacterial Hemostasis
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