维生素D滴剂联合双C方案对妊娠期糖尿病患者血糖及母婴结局的影响

Effect of Vitamin D Drops Combined with Double C Regimen on Blood Glucose and Maternal and Infant Outcomes in Patients with Gestational Diabetes Mellitus

目的 分析妊娠期糖尿病患者接受维生素D滴剂联合双C方案的干预效果。方法 回顾性选取2023年6月—2024年2月泉州市第一医院收治的98例妊娠期糖尿病患者的临床资料,以治疗方案的不同分对照组、观察组,各49例。对照组实施双C干预,观察组在对照组基础上联合维生素D滴剂治疗。对比两组血糖指标、胰岛功能、母婴结局。结果 干预后,观察组餐后2 h血糖、空腹血糖、胰岛素抵抗指数、不良母婴结局发生率均低于对照组,胰岛素分泌指数高于对照组,差异有统计学意义(P均<0.05)。结论 双C方案联合维生素D滴剂协同干预能够改善妊娠期糖尿病患者的胰岛素分泌、血糖水平,有效遏制不良母婴结局的发生。

Objective To analyze the intervention effect of vitamin D drops combined with double C regimen in pa-tients with gestational diabetes mellitus.Methods The clinical data of 98 patients with gestational diabetes mellitus admitted to Quanzhou First Hospital from June 2023 to February 2024 were retrospectively selected and divided into control group and observation group according to different treatment schemes,with 49 cases in each group.The con-trol group was treated with double C intervention,and the observation group was treated with vitamin D drops on the basis of the control group.The blood glucose index,islet function,maternal and infant outcomes were compared be-tween the two groups.Results After intervention,the 2-hour postprandial plasma glucose,fasting plasma glucose,in-sulin resistance index and the incidence of adverse maternal and infant outcomes in the observation group were lower than those in the control group,and the insulin secretion index was higher than that in the control group,the differ-ences were statistically significant(all P<0.05).Conclusion Double C regimen combined with vitamin D drops can im-prove insulin secretion and blood glucose level in patients with gestational diabetes mellitus,and effectively curb the occurrence of adverse maternal and infant outcomes.