预防性补充钾、镁离子对急性心肌梗死患者PCI术后室性心律失常的预防效果

Preventive Effect of Preventive Supplement of Potassium and Magnesium Ions on Ventricular Arrhythmia After PCI in Patients with Acute Myocardial Infarction

目的探讨预防性补充钾、镁离子对急性心肌梗死(AMI)患者经皮冠状动脉介入(PCI)术后室性心律失常的预防效果。方法290例行PCI治疗的AMI患者根据术后治疗措施的不同分为两组,对照组术后给予常规治疗,观察组术后在对照组基础上给予门冬氨酸钾镁注射液治疗,比较两组的室性心律失常发生率、不良预后发生情况。结果治疗1周、1个月、2个月后,观察组的室性心律失常发生率均明显低于对照组(P<0.05)。治疗1个月后,两组的心力衰竭、复发性心绞痛发生率比较,差异无统计学意义(P>0.05);观察组的再梗死发生率明显低于对照组(P<0.05)。结论AMI患者PCI术后预防性补充钾、镁离子可明显降低其室性心律失常发生风险,减少再梗死的发生。

Objective To explore the preventive effect of preventive supplement of potassium and magnesium ions on ventricular arrhythmia after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods 290 AMI patients treated with PCI were divided into two groups according to different postoperative treatment measures.After surgery,the control group was given routine treatment,and the observation group was treated with potassium aspartate and magnesium aspartate injection on the basis of the control group.The incidence of ventricular arrhythmia and occurrence of adverse prognosis were compared between the two groups.Results After 1 week,1 month and 2 months of treatment,the incidences of ventricular arrhythmia in the observation group were significantly lower than those in the control group(P<0.05).After 1 month of treatment,no significant difference was found in the incidences of heart failure and recurrent angina pectoris between the two groups(P>0.05),while the incidence of re-infarction in the observation group was significantly lower than that in the control group(P<0.05).Conclusions Preventive supplement of potassium and magnesium ions after PCI in patients with AMI can obviously reduce the occurrence risk of ventricular arrhythmia and reduce the occurrence of re-infarction.