GBR术结合PRF治疗美学区前牙缺损的效果

Effect of GBR Combined with PRF in the Treatment of Anterior Tooth Defect in Aesthetic Area

目的探讨引导骨再生(GBR)术结合富血小板纤维蛋白(PRF)对美学区前牙缺损患者牙槽嵴骨量及牙槽骨骨密度的影响。方法以焦作煤业(集团)有限责任公司中央医院2017年1月至2021年12月诊治的美学区前牙缺损患者68例作为研究对象,按照随机分组原则,将以上患者分为研究组以及对照组,所有患者均接受前牙缺损区种植牙手术联合GBR术进行治疗,研究组患者在此基础上采取PRF进行治疗。比较两组患者的种植区牙槽骨骨壁厚度、术后6个月牙槽骨的吸收量、美学指标、外观美观性、牙槽骨密度之间的差异。结果治疗后,研究组患者的种植区1、7、10 mm处的牙槽骨骨壁厚度均高于对照组(P<0.05);研究组患者的美学指数评分高于对照组(P<0.05)。研究组患者的排列整齐、覆盖完整、咬合正常率高于对照组(P<0.05)。治疗后1、3、6个月,研究组患者的牙槽骨密度高于对照组(P<0.05)。结论美学区前牙缺损患者采取GBR术结合PRF引导骨再生治疗,患者牙槽嵴骨量、牙槽骨骨密度及美学指标显著改善,建议临床推广。

Objective To investigate the effects of guided bone regeneration(GBR)combined with platelet rich fibrin(PRF)on alveolar ridge bone mass and alveolar bone mineral density in patients with aesthetic anterior tooth defects.Methods A total of 68 patients with anterior tooth defect in aesthetic area diagnosed and treated in Jiaozuo Coal Industry(Group)Co.,Ltd.Central Hospital from January 2017 to December 2021 were selected as the study objects.According to the principle of randomization,the above patients were divided into study group and control group.All patients received dental implant surgery in anterior tooth defect area combined with GBR.The patients in the study group were treated with PRF on this basis.The bone wall thickness of implant area alveolar bone,absorption of alveolar bone at 6 months after surgery,aesthetic index,aesthetic appearance and alveolar bone density were compared between the two groups.Results After treatment,the bone wall thickness of alveolar bone at 1,7 and 10 mm of planting area in study group were higher than those in control group(P<0.05).The aesthetic index score of the study group was higher than that of the control group(P<0.05).The rate of orderly arrangement,complete coverage and normal occlusion in study group were higher than those in control group(P<0.05).At 1,3 and 6 months after treatment,the alveolar bone mineral density of the study group were higher than those of the control group(P<0.05).Conclusion GBR combined with PRF guided bone regeneration can significantly improve the alveolar ridge bone mass,bone mineral density and aesthetic indexes in patients with anterior tooth defect in aesthetic area,suggesting clinical promotion.