复合益生菌制剂对母猪繁殖性能及免疫力的影响

Effects of compound probiotics on the reproductive performance and immunity of sows

试验旨在研究不同水平的复合益生菌制剂对母猪繁殖性能及免疫功能的影响,确定母猪生产中益生菌制剂的最适添加水平。试验选择胎次为2~3胎的妊娠期60 d的妊娠母猪40头,按照单因素试验设计原则,将其分成4组,每个重复1头妊娠母猪。对照组妊娠母猪饲喂基础饲料(不添加复合益生菌制剂),试验组1~3分别在基础饲料中添加250、500和1000 mg/kg的复合益生菌制剂。试验周期从妊娠第60天至产后21 d。结果显示,母猪饲喂500 mg/kg和1000 mg/kg的复合益生菌制剂增加了产活仔数和健仔数(P<0.05),降低了死胎数(P<0.05);提高了初生仔猪个体平均重、断奶个体平均重、平均日增重及断奶成活率(P<0.05)。所有复合益生菌制剂组仔猪的腹泻率均显著降低,分别比对照组降低了27.11%、52.85%、57.86%(P<0.05)。母猪饲喂250、500和1000 mg/kg的复合益生菌制剂可以显著增加球蛋白A水平(P<0.05),母猪饲喂500和1000 mg/kg的复合益生菌制剂可以显著增加球蛋白G和球蛋白M水平(P<0.05)。母猪饲喂250、500和1000 mg/kg的复合益生菌制剂可以显著降低肿瘤坏死因子-α水平(P<0.05),母猪饲喂500和1000 mg/kg的复合益生菌制剂可以显著增加白细胞介素-10水平(P<0.05)。综上所述,妊娠期母猪饲喂复合益生菌制剂可以提高母猪的繁殖性能和机体免疫功能,改善仔猪生长性能,复合益生菌制剂的最适添加水平为500~1000 mg/kg。

This experiment was conducted to investigate the effects of different levels of compound probiotics on reproductive performance and immune function of sows,and to determine the optimal supplemental level of probiotics in sow production.Forty pregnant sows with a gestation period of 60 days with a parity of 2-3 fetuses were selected and divided into 4 groups with 1 pregnant sow per replicate according to the single-factor experimental design principle.The pregnant sows in the control group were fed a basic diet(without any compound probiotics),and the pregnant sows in experimental groups 1 to 3 were fed a basic diet supplemented with 250 mg/kg,500 mg/kg and 1,000 mg/kg compound probiotics,respectively.The test period was from the 60th day of gestation to the day 21 post-parturition.The results showed that 500 mg/kg and 1000 mg/kg compound probiotics increased the number of live and healthy piglets(P<0.05),and decreased the number of stillbirths(P<0.05).The average weight of newborn piglets,average weight of the weaned,average daily gain,and survival rate of the weaned were all improved(P<0.05).The diarrhea rate of piglets in all compound probiotics groups was significantly reduced,which was 27.11%,52.85%and 57.86%lower in comparison with the control group,respectively(P<0.05).The level of globulin A was significantly higher among sows fed with 250 mg/kg,500 mg/kg and 1000 mg/kg probiotics(P<0.05),while the levels of globulin G and M were significantly raised among sows fed with 500 mg/kg and 1000 mg/kg probiotics(P<0.05).The level of TNF-αwas significantly lowered among sows fed with 250 mg/kg,500 mg/kg and 1000 mg/kg compound probiotics(P<0.05),while the level of interleukin-10 was significantly higher among sows fed with 500 mg/kg and 1000 mg/kg compound probiotics(P<0.05).In conclusion,feeding pregnant sows with compound probiotics could improve their reproductive performance and immunity as well as the growth performance of piglets.The optimal supplemental level of compound probiotics is determined as 500-1000 mg/kg.