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黄连阿胶汤加减联合自制安神睡眠贴治疗失眠患者效果及对睡眠质量指数的影响

Effect of Modified Huanglian Ass Hide Glue Decoction Combined with Self-made Anshen Sleeping Paste on Insomnia Patients and Its Influence on Sleep Quality Index
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摘要 目的:研究使用中药方剂黄连阿胶汤联合自制安神睡眠贴治疗失眠患者临床疗效及对其睡眠质量指数的影响。方法:选取2021年1月到2023年12月在我院接受治疗103失眠患者,随机数表法分为对照组(51例)和研究组(52例),对照组患者予以常规西药治疗,研究组患者在常规西药治疗的基础上加用黄连阿胶汤联合自制安神睡眠贴进行治疗,比较两组患者临床治疗疗效、治疗前后睡眠质量指数(PSQI)和生活质量(QOL)总分,以及治疗后全睡眠时间和睡眠觉醒次数。结果:研究组治疗后临床疗效有效率高于对照组(P<0.05)。两组患者治疗后PSQI总分均显著下降和QOL总分均上升,并且研究组与对照组比较有相同趋势(P<0.05)。治疗后,研究组患者全睡眠时间显著高于对照组患者(P<0.05),而睡眠觉醒次数显著低于对照组患者(P<0.05)。结论:黄连阿胶汤联合自制安神睡眠贴对失眠患者具有很好的临床治疗疗效,并且有助于降低其睡眠指数和提高生活质量,值得进行临床推广。 Objective:To study the clinical efficacy of Huanglian ass hide glue Decoction combined with self-made Anshen Sleeping Paste in the treatment of insomnia patients and its influence on their sleep quality index.Methods:103 insomniacs who were treated in our hospital from January 2021 to December 2023 were randomly divided into the control group(51 cases)and the research group(52 cases).The patients in the control group were treated with conventional western medicine.The patients in the research group were treated with Huanglian ass hide glue Decoction combined with self-made Anshen Sleep Paste on the basis of conventional western medicine.The clinical treatment efficacy,total scores of sleep quality index(PSQI)and quality of life(QOL)before and after treatment,as well as the total sleep time and sleep wake times after treatment of the two groups were compared.Results:The clinical efficacy of the study group was higher than the control group(P<0.05).PSQI scores and QOL scores decreased after treatment,and the same trend was observed between study and control groups(P<0.05).After treatment,the total sleep duration was higher than the control patients(P<0.05),while the number of sleep arousals was lower than the control patients(P<0.05).Conclusion:Huanglian ass hide glue Decoction combined with self-made Anshen Sleeping Paste has a good clinical therapeutic effect on insomnia patients,and it helps to reduce their sleep index and improve their quality of life,which is worthy of clinical promotion.
作者 蔡巍巍 杜莹莹 刘珊珊 刘轶菲 夏伟 CAI Wei-wei;DU Ying-ying;LIU Shan-shan;LIU Yi-fei;XIA Wei(Department of Traditional Chinese Medicine,Jiangning Hospital Affiliated to Nanjing Medical University,Nanjing,Jiangsu,211100,China)
出处 《现代生物医学进展》 CAS 2024年第17期3237-3240,3364,共5页 Progress in Modern Biomedicine
基金 第七批全国老中医药专家学术经验继承工作项目(国中医药人教发[2022]76号)。
关键词 黄连阿胶汤 安神睡眠贴 失眠 睡眠质量指数 生活质量 Huanglian ass hide glue Decoction Huanglian ass hide glue Decoction Insomnia Sleep quality index Quality of life
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