玫瑰痤疮患者生活质量、心理状况和治疗需求调查

Survey of the quality of life,psychological status,and treatment needs of patients with rosacea

目的探讨玫瑰痤疮对患者生活质量和心理健康的影响,分析不同亚型、性别、日晒情况、吸烟情况、民族、学历等因素的差异;以及患者对治疗的需求。方法该研究为横断面调查。纳入2022年10月至2024年1月,昆明医科大学第一附属医院皮肤科就诊的玫瑰痤疮患者177例,男36例,女141例,年龄35(29,44)岁。对患者进行问卷调查,内容包括一般资料、皮肤病生活质量指数(DLQI)、广泛性焦虑量表(GAD-7)、健康问卷抑郁量表(PHQ-9)、患者治疗需求(PNQ)等内容。对收集的数据进行统计分析。结果患者DLQI评分中位数为10(3,15)分,为中度影响;GAD-7评分中位数为5(2,7)分,为轻度焦虑;PHQ-9评分中位数为6(2,9)分,为轻微抑郁症。女性DLQI和GAD-7评分高于男性(均P<0.05),丘疹脓疱型DLQI和GAD-7评分高于其他亚型(均P<0.01),低学历患者DLQI和GAD-7评分高于高学历患者(均P<0.01),非吸烟患者GAD-7评分高于吸烟患者(P<0.05)。DLQI和PHQ-9评分呈正相关(r=0.39,P<0.01);DLQI和GAD-7评分呈正相关(r=0.51,P<0.01);PHQ-9和GAD-7评分呈正相关(r=0.59,P<0.01)。在治疗需求方面,159例(89.8%)患者强烈希望获得明确的诊疗方案,159例(89.8%)患者希望治愈所有皮肤病变。28项治疗需求问卷显示,女性的每一项治疗需求比例均高于男性(均P<0.05)。结论玫瑰痤疮对患者生活质量和心理健康造成显著影响,特别是对女性、丘疹脓疱型患者和低学历患者。多数患者对明确的诊断和治疗方案以及治愈所有皮肤病变有强烈需求,且女性患者需求更为突出。

ObjectiveTo investigate the impact of rosacea on patients'quality of life and mental health,and to analyze variations across different subtypes,gender,sun exposure,smoking status,ethnicity,and educational levels,as well as patients'demands for treatment.MethodsIt was a cross-sectional study from October 2022 to January 2024,177 rosacea patients from the Department of Dermatology,the First Affiliated Hospital of Kunming Medical University were surveyed.The cohort comprised 36 males and 141 females,with a median age of 35(29,44)years.Data collected through questionnaires included general information,Dermatology Life Quality Index(DLQI),Generalized Anxiety Disorder-7(GAD-7),Patient Health Questionnaire-9(PHQ-9),and Patient Need Questionnaire(PNQ).Statistical analysis was conducted on the collected data.ResultsThe median DLQI score was 10(3,15),indicating moderate impact.The median GAD-7 score was 5(2,7),suggesting mild anxiety;while the median PHQ-9 score was 6(2,9),indicating mild depression.Female patients scored higher in both DLQI and GAD-7 than males(P<0.05).Papulopustular subtypes had higher DLQI and GAD-7 scores compared to other subtypes(P<0.01).Patients with lower education levels scored higher in DLQI and GAD-7 than those with higher education(P<0.01),and non-smokers had higher GAD-7 scores than smokers(P<0.05).Significant positive correlations were found between DLQI and PHQ-9(r=0.39,P<0.01),and DLQI and GAD-7(r=0.51,P<0.01),as well as between PHQ-9 and GAD-7(r=0.59,P<0.01).Regarding treatment needs,159 patients(89.8%)expressed a strong desire for a clear diagnosis and treatment plan,and the same number wished for a complete resolution of all skin lesions.Female patients consistently demonstrated significantly stronger demands in all 28 treatment need items(all P<0.05).ConclusionsRosacea significantly affects patients'quality of life and mental health,particularly among females,individuals with papulopustular subtypes,and those with lower education levels.There is a strong demand for definitive diagnostic and therapeutic plans,especially among female patients.