急性ST段抬高型心肌梗死患者非罪犯病变血运重建时机的研究进展

Progress on the Timing of Non- culprit Lesion Revascularization in Patients with Acute ST- Segment Elevation Myocardial Infarction

急性ST段抬高型心肌梗死是冠心病最高危的一类,合并多支血管病变者预后更差。早期开通梗死相关动脉,恢复心肌组织的血液灌注,可显著降低急性期死亡率,并改善患者远期预后。对于成功完成梗死相关动脉血运重建的患者,目前已有充足的证据证明非梗死相关动脉的完全性血运重建优于单纯罪犯病变血运重建,然而血运重建的时机目前尚无定论。本文拟就急性ST段抬高型心肌梗死患者非罪犯病变血运重建时机的研究进展进行综述。

ST-segment elevation myocardial infarction is the most high-risk cohort in patients with coronary heart disease,and those with multi-vessel disease have worse prognosis.Timely opening infarct-related arteries and restoring myocardial perfusion will significantly reduce short-term mortality and improve long-term prognosis.For patients who have achieved infarct-related artery revascularization successfully,the superiority of complete revascularization evidence has been confirmed,compared with culprit-lesion revascularization alone,but the timing of revascularization remains underdetermined.The current review will focus on the timing for non-culprit lesion revascularization in patients with ST-segment elevation myocardial infarction.