植物CaMs/CMLs家族研究进展

Research progress of CaMs/CMLs family in plant

钙离子作为真核细胞中重要的第二信使,介导了真核生物对几乎所有环境和发育相关刺激信号的响应。在长期进化过程中,植物进化出多种钙信号解码器以实现细胞对特异刺激作出恰当的响应。钙调素(calmudulins, CaMs)与类钙调蛋白(calmodulin-like proteins, CMLs)家族蛋白是Ca^(2+)感受器,在植物生长发育和胁迫抗性中发挥重要调控作用。本文总结了植物CAMs/CMLs家族蛋白的结构、遗传进化、作用机制、生物学功能等方面的最新研究进展,以期为钙信号网络研究提供参考。

As a vital second messenger in eukaryotic cell,Ca^(2+)almost participates in the transduction of all stimuli signals related to environment,growth and development.Various Ca^(2+)decoders are evolved and confer plants to respond to these stimuli specifically and appropriately.Calmudulins/calmodulin-like proteins(CaMs/CMLs)family,which is considered as Ca^(2+)sensor,plays important roles in plant growth and stress resistance.This paper reviews the current research progress on the protein structure,genetic evolution,biological functions and acting molecular mechanism of CaMs/CMLs family,so as to provide reference for the further research of Ca^(2+)signaling.