摘要
Metronidazole(MNZ)is a type of antibiotic that can help people and animals cure bacterial in fections,however,abuse of MNZ has posed a threat to human health.Hence,portable and vi sual detection of MNZ is meaningful for food safety and rational administration of drugs,bu full of challenges.Hence,a porous three-dimensional Tb-based metal-organic framework(MOF{(CH_(3))_(2)NH_(2)·[Tb_(5)(TDA)_(8)(H_(2)O)_(2)]·6DMF·2C_(2)H_(5)OH}_n(TDA-Tb)with good solvent and p H stabilities was pre pared,and the framework possesses one-dimensional channels with a diameter of 12 A along the c-axis Experiment results suggest that the synthesized TDA-Tb can selectively and sensitively detect MNZ in water,and the limit of detection(LOD)is as low as 4.1×10^(-7)mol/L.Moreover,a flexible sensor TDA Tb-M was also constructed by incorporating TDA-Tb into membrane materials for convenient usage.And the TDA-Tb-M firstly realized portable and visual detection of MNZ through smartphone scanning,which may inspire more probes with wide application ranges.
基金
supported by the National Natural Science Foundation of China(Nos.92161202,21971125,22101138,21625103,and22121005)
The Fundamental Research Funds for the Central Universities(No.D5000230371)。
