超声引导下微波消融术与微创旋切术治疗乳腺良性结节患者的效果比较

Comparison of effects of ultrasound-guided microwave ablation and minimally invasive circumcision in treatment of patients with benign breast nodules

目的:比较超声引导下微波消融术与微创旋切术治疗乳腺良性结节患者的效果。方法:回顾性分析2020年1月至2024年3月该院收治的80例乳腺良性结节患者的临床资料,按照手术方法不同将其分为对照组和观察组各40例。对照组实施超声引导下微创旋切术治疗,观察组实施超声引导下微波消融术治疗,比较两组围术期指标水平、乳房美观优良率、手术前后炎性因子[白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)]水平、术后1个月并发症发生率和复发率。结果:观察组切口愈合时间和手术时间均短于对照组,切口长度小于对照组,差异有统计学意义(P<0.05);两组住院时间比较,差异无统计学意义(P>0.05);两组乳房美观优良率比较,差异无统计学意义(P>0.05);术后,两组IL-6、TNF-α和CRP水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为5.00%(2/40),低于对照组的25.00%(10/40),差异有统计学意义(P<0.05);两组复发率比较,差异无统计学意义(P>0.05)。结论:超声引导下微波消融术治疗乳腺良性结节患者可缩短切口愈合时间、手术时间,减小切口长度,降低炎性因子水平和并发症发生率,效果优于超声引导下微创旋切术治疗。

Objective:To compare effects of ultrasound-guided microwave ablation and minimally invasive circumcision in treatment of patients with benign breast nodules.Methods:The clinical data of 80 patients with benign breast nodules admitted to this hospital from January 2020 to March 2024 were retrospectively analyzed.According to different surgical methods,they were divided into control group and observation group,40 cases in each group.The control group was treated with ultrasound-guided minimally invasive circumcision,while the observation group was treated with ultrasound-guided microwave ablation.The perioperative index levels,the excellent and good rate of breast aesthetics,the levels of inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)]before and after the surgery,the incidence of complications,and the recurrence rate 1 month after the surgery were compared between the two groups.Results:The incision healing time and the operation time of the observation group were shorter than those of the control group,the incision length was smaller than that of the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in hospitalization time between the two groups(P>0.05);There was no statistically significant differencen in the rate of excellent breast beauty between the two groups(P>0.05);After the surgery,the levels of IL-6,TNF-αand CRP in the two groups were higher than those before the surgery,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 5.00%(2/40),which was lower than 25.00%(10/40)in the control group,and the difference was statistically significant(P<0.05).However,there was no significant difference in the recurrence rate between the two groups(P>0.05).Conclusions:Ultrasound-guided microwave ablation for the patients with benign breast nodules can shorten the incision healing time and the operation time,reduce the incision length,and reduce the levels of inflammatory factors and the incidence of complications.Moreover,it is superior to ultrasound-guided minimally invasive circumcision.