摘要
More than 4 years has elapsed since the World Health Organization(WHO)officially announced the coronavirus disease 2019(COVID-19)as a pandemic outbreak in March 11,2020.Despite the ongoing investigations and political debates upon the origin,exacerbation,resurgence,andfinal control of COVID-19,medical and scientific consensus indicates that the now endemic COVID-19 virus is one of the worst public health crises in our lifetime.Almost every person on earth has been directly or indirectly impacted by the adverse effects of the highly contagious viral pathogen-SARS-CoV-2(severe acute respiratory syndrome coronavirus 2).Indeed,the population reach of the COVID-19 infection includes governmental response measures(e.g.,lockdowns and social distancing,mandates for masks and face coverings,vaccines,etc.)that have restricted entrenched societal routines,personal mobility,and lifestyles.Unfortunately,the host of health problems linked to this viral infection linger to this day,with selective groups of people experiencing a higher risk for untoward medical outcomes and/or elevated levels of vulnerability to the post-acute sequelae of COVID-19(i.e.long-COVID).For example,a 2021 study by Logue et al.provided initial evidence that 10%–30%of individuals in United States may experience prolonged symptoms following SARS-CoV-2 infection,including cardiovascular abnormalities.1 Similarly,a 2021 retrospective cohort study in England suggest that the incidence of major adverse cardiovascular events(e.g.heart failure,myocardial infarction,ischemic stroke.
